BPGM Antibody (F-2): sc-376578
- BPGM Antibody (F-2) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 89-123 within an internal region of BPGM of human origin
- recommended for detection of BPGM of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BPGM Antibody (F-2). This work is in progress.
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SEE ALSO...
BPGM Antibody (F-2) is a mouse monoclonal IgM antibody that detects BPGM (2,3-bisphosphoglycerate mutase) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BPGM is a 259 amino acid protein that belongs to the phosphoglycerate mutase family and functions as a homodimer, playing a vital role in the regulation of hemoglobin oxygen affinity. By catalyzing the conversion of 3-phospho-D-glyceroyl phosphate to 2,3-bisphospho-D-glycerate (2,3-BPG), BPGM is essential for maintaining the appropriate concentration of 2,3-BPG within the cell, which is crucial for facilitating oxygen release from hemoglobin in red blood cells. This regulation is particularly important under conditions of low oxygen, as it allows for enhanced oxygen delivery to tissues. The gene encoding BPGM is located on human chromosome 7, a region that contains over 1,000 genes and is implicated in various genetic disorders, including Osteogenesis imperfecta and Williams-Beuren syndrome. Anti-BPGM antibody (F-2) is an invaluable tool for researchers studying oxygen transport and related pathologies, providing reliable detection and analysis of this critical protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BPGM Antibody (F-2) | sc-376578 | 200 µg/ml | $322.00 | |||
BPGM (F-2) Neutralizing Peptide | sc-376578 P | 100 µg/0.5 ml | $69.00 |