Anti-BoNT/B Antibody (GR-3G7) is a mouse monoclonal IgG1 (kappa light chain) BoNT/B antibody provided at 200 µg/ml
raised against BoNT/B of Clostridium botulinum origin
BoNT/B Antibody (GR-3G7) is recommended for detection of BoNT/B of Clostridium botulinum origin by FCM and ELISA
Anti-BoNT/B Antibody (GR-3G7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of BoNT/B (GR-3G7): sc-101376.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
BoNT/B Antibody (GR-3G7) is a high quality monoclonal BoNT/B antibody (also designated BoNT/B antibody) suitable for the detection of the BoNT/B protein of Clostridium botulinum origin. BoNT/B Antibody (GR-3G7) is available as both the non-conjugated anti-BoNT/B antibody form, as well as multiple conjugated forms of anti-BoNT/B antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Botulism is a rare but serious paralytic illness caused by a nerve toxin, which is produced by the bacterium Clostridium botulinum. This neuromuscular disorder occurs through an exquisite series of molecular events, ultimately ending with the arrest of acetylcholine release, resulting in flaccid paralysis. BoNT/B (Botulinum neurotoxin type B), also known as Bontoxilysin B or botB, is a highly toxic 1,291 amino acid secreted protein that exists as a disulfide-linked heterodimer of a heavy chain (H) and a light chain (L). Using zinc as a cofactor, BoNT/B functions as an endopeptidase that cleaves various neuronal proteins, such as VAMP-2, thereby preventing neurotransmitter release. BoNT/B binds to neuronal synapses and is internalized and transported to the spinal cord, where it inserts itself between presynaptic and postsynaptic neurons, inhibiting neurotransmitter release and causing paralysis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
What is the recommended secondary reagent to be used with sc-101376: BoNT/B (GR-3G7) mouse monoclonal primary?
Asked by: Randy McDonald
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here:
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn