BoNT/A Antibody (KBA468): sc-51775
- BoNT/A Antibody (KBA468) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against BoNT/A of Clostridium botulinum origin
- recommended for detection of BoNT/A of Clostridium botulinum origin by ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BoNT/A Antibody (KBA468). This work is in progress.
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BoNT/A Antibody (KBA468) is a mouse monoclonal IgG2a antibody that detects Botulinum neurotoxin type A in Clostridium botulinum by enzyme-linked immunosorbent assay (ELISA). BoNT/A is a highly potent neurotoxin produced by the bacterium Clostridium botulinum, known for causing severe paralysis by inhibiting acetylcholine release at the neuromuscular junction. This inhibition occurs through selective cleavage of SNAP-25, a vital protein in the exocytotic machinery facilitating neurotransmitter release. BoNT/A exists as a dimer in aqueous solution, which is crucial for enzymatic activity and stability. Understanding BoNT/A′s structural characteristics aids in developing therapeutic applications, such as treating involuntary muscle disorders and chronic pain, while enhancing the design of effective diagnostic tools. Anti-BoNT/A antibody (KBA468) serves as an essential resource for researchers studying botulinum neurotoxin action and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BoNT/A Antibody (KBA468) | sc-51775 | 100 µg/ml | $322.00 |