BoNT/A Antibody (24A29): sc-66099
- BoNT/A Antibody (24A29) is a mouse monoclonal IgM provided at 100 µg/ml
- raised against BoNT/A of Clostridium botulinum origin
- recommended for detection of BoNT/A of Clostridium botulinum origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BoNT/A Antibody (24A29). This work is in progress.
BoNT/A Antibody (24A29) is a mouse monoclonal IgM antibody that detects Botulinum neurotoxin type A (BoNT/A) of Clostridium botulinum by western blotting (WB). BoNT/A is a highly potent neurotoxin known for causing paralysis by inhibiting acetylcholine release at the neuromuscular junction, making BoNT/A a critical target for both research and therapeutic applications. BoNT/A exists as a dimer in aqueous solution, which is essential for biological activity. This dimerization enables effective cleavage of SNAP-25, a key protein involved in neurotransmitter exocytosis. Understanding BoNT/A structural characteristics aids in developing therapeutic agents for muscle disorders and enhances knowledge of BoNT/A mechanism of action, vital for creating effective antidotes and treatments for botulism. Anti-BoNT/A antibody (24A29) serves as an invaluable tool for researchers studying molecular mechanisms of this neurotoxin and nervous system interactions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BoNT/A Antibody (24A29) | sc-66099 | 100 µg/ml | $322.00 |