
BMP-4 Antibody (9H4) is a mouse monoclonal IgG2b antibody that detects BMP-4 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). BMP-4, also known as BMP-2B, is a critical member of the bone morphogenetic protein (BMP) family, which is part of the transforming growth factor-beta (TGFβ) superfamily. BMP-4 plays a vital role in the regulation of bone and cartilage development, particularly during embryogenesis. BMP-4 is primarily located in the extracellular matrix and is secreted by various cell types, where BMP-4 interacts with specific receptors on target cells to initiate signaling pathways that lead to cellular differentiation and tissue formation. BMP-4′s location in the extracellular matrix enables influence over the local microenvironment, thereby modulating the behavior of surrounding cells and contributing to the intricate processes of skeletal development and repair. Additionally, BMP-4 has been shown to interact with other BMP family members, such as BMP-2 and BMP-7, which can further enhance biological effects and underscore significance in developmental biology and regenerative medicine. Anti-BMP-4 antibody (9H4) is an essential tool for researchers studying these complex signaling pathways and their implications in various physiological and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BMP-4 Antibody (9H4) | sc-81000 | 200 µg/ml | $322.00 |