Blood Group B antigen Antibody (HEB-29): sc-59463
- Blood Group B antigen Antibody (HEB-29) is a mouse monoclonal IgM provided at 500 µl supernatant
- raised against a mixture of erythrocytes of blood group B and glycoprotein fraction isolated from the saliva of secretors with blood group B of human origin
- recommended for detection of Blood Group B Antigen of human origin by IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Blood Group B antigen Antibody (HEB-29). This work is in progress.
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Blood Group B antigen Antibody (HEB-29) is a mouse monoclonal IgM antibody that detects Blood Group B Antigen of human origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Blood Group B antigen antibody (HEB-29) is available in non-conjugated form. Blood Group B antigen is a crucial component of the ABO blood group system, playing a significant role in transfusion medicine and organ transplantation. Blood Group B antigen is primarily located on the surface of erythrocytes and certain epithelial cells, formed by adding specific sugar residues to precursor molecules. Blood Group B antigen presence is vital for determining blood compatibility, as mismatched transfusions can lead to severe immune reactions. Blood Group B antigen expression can be modulated during malignant transformation, potentially influencing tumor immunology and patient outcomes. Understanding Blood Group B antigen distribution and function is essential for both clinical applications and research into immune response and disease progression mechanisms.
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Blood Group B antigen Antibody (HEB-29) References:
- Development of H activity by human blood-group B substance treated with coffee bean alpha-galactosidase. | WATKINS, WM., et al. 1962. Nature. 195: 1204-6. PMID: 14005253
- Isolation of a B-specific disaccharide from human blood-group B substance. | PAINTER, TJ., et al. 1962. Nature. 193: 1042-4. PMID: 14483250
- Loss of blood-group-B antigen in chronic lymphatic leukaemia. | RICHARDS, AG. 1962. Lancet. 2: 178-9. PMID: 14491924
- Bifidobacterial α-galactosidase with unique carbohydrate-binding module specifically acts on blood group B antigen. | Wakinaka, T., et al. 2013. Glycobiology. 23: 232-40. PMID: 23089618
- Suppressed expression of blood group B antigen and blood group galactosyltransferase in a preleukemic subject. | Yoshida, A., et al. 1985. Blood. 66: 990-2. PMID: 3929862
- Immunochemical studies on blood groups. LII. Structures and activities of oligosaccharides produced by alkaline degradation of a blood group B substance previously subjected to partial hydrolysis by dilute hydrochloric acid. | Lundblad, A., et al. 1972. Arch Biochem Biophys. 148: 291-303. PMID: 4110197
- Normal blood group B antigen and B transferase activity in a patient with IgM autoanti-B agglutinin. | Lopez, M., et al. 1978. Vox Sang. 34: 18-21. PMID: 414449
- Expression of a blood group B antigen-related glycoepitope in human dorsal root ganglion cells. | Yamada, M., et al. 1994. J Neurol Sci. 126: 178-83. PMID: 7531759
- Sandwich capture enzyme immunoassay for water soluble blood group B substance in secretor saliva. | Yukawa, N., et al. 1995. J Immunoassay. 16: 247-61. PMID: 7593648
- A monoclonal IgM kappa from a blood group B individual with specificity for alpha-galactosyl epitopes on partially hydrolyzed blood group B substance. | Nickerson, KG., et al. 1993. Carbohydr Res. 243: 345-57. PMID: 7688662
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Blood Group B antigen Antibody (HEB-29) | sc-59463 | 500 µl supernatant | $316.00 |