BIN2 Antibody (F-12): sc-376691

BIN2 Antibody (F-12) is a mouse monoclonal IgG2a light chain antibody that detects BIN2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that plays a crucial role in cellular processes, particularly in hematopoietic tissues, where BIN2 is predominantly expressed in the spleen, thymus, colon, placenta, and various lymphoid and granulocytic cells. BIN2 is characterized by interaction with BIN1, another BAR protein, and while BIN1 is recognized for tumor suppressor functions, BIN2 does not share these features, highlighting a distinct role in cellular dynamics. Notably, BIN2 is produced in two isoforms due to alternative splicing, which may contribute to functional diversity in different cellular contexts. BIN2′s ability to interact with other proteins and specific expression patterns make BIN2 an important target for research into hematopoietic cell function and potential implications in cancer biology. anti-BIN2 antibody (F-12) is an essential tool for researchers aiming to explore the intricate roles of BIN2 in various biological processes.

The preferred BIN2 antibody is BIN2 Antibody (E-2): sc-376391.