βB3-crystallin Antibody (G-3): sc-374374

βB3-crystallin Antibody (G-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects βB3-crystallin of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-βB3-crystallin antibody (G-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. βB3-crystallin plays a crucial role in maintaining the structural integrity and transparency of the eye lens, which is essential for proper vision. Located primarily in the lens fibers, βB3-crystallin contributes to the refractive properties of the lens by forming a highly organized structure that minimizes light scattering. This organization is vital for optimal visual acuity, as any disruption in the crystallin structure can lead to cataract formation and impaired vision. βB3-crystallin′s ability to form dimers and higher-order aggregates is essential for its function, as this property allows for the stabilization of the lens architecture under varying physiological conditions. With diverse applications in research and diagnostics, βB3-crystallin monoclonal antibody (G-3) serves as an invaluable tool for studying crystallins in lens biology and related ocular diseases.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

βB3-crystallin Antibody (G-3) References:

1. The short 5' untranslated region of the betaA3/A1-crystallin mRNA is responsible for leaky ribosomal scanning.  |  Werten, PJ., et al. 1999. Mol Biol Rep. 26: 201-5. PMID: 10532316
2. Structure of the crystallins.  |  Slingsby, C. and Clout, NJ. 1999. Eye (Lond). 13 (Pt 3b): 395-402. PMID: 10627816
3. Alpha-crystallin.  |  Horwitz, J. 2003. Exp Eye Res. 76: 145-53. PMID: 12565801
4. Desminopathies in muscle disease.  |  Paulin, D., et al. 2004. J Pathol. 204: 418-27. PMID: 15495235
5. Transparency and non-refractive functions of crystallins--a proposal.  |  Bhat, SP. 2004. Exp Eye Res. 79: 809-16. PMID: 15642317
6. Beta-crystallin association.  |  Hejtmancik, JF., et al. 2004. Exp Eye Res. 79: 377-83. PMID: 15669142
7. Beta A3/A1-crystallin association: role of the N-terminal arm.  |  Hope, JN., et al. 1994. Protein Eng. 7: 445-51. PMID: 8177894
8. Association properties of betaB2- and betaA3-crystallin: ability to form dimers.  |  Hejtmancik, JF., et al. 1997. Protein Eng. 10: 1347-52. PMID: 9514125

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-βB3-crystallin Antibody (G-3) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-βB3-crystallin Antibody (G-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

βB3-crystallin Antibody (G-3) Specifications

Alternate Product Name: βB3-crystallin

Product Clone Name: G-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 99-137

Epitope Target: βB3-crystallin

Epitope Species: human

Product Reactivity/Detection: βB3-crystallin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for βB3-crystallin Antibody (G-3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred βB1-crystallin antibody is βB1-crystallin Antibody (H-3): sc-48335.