beta Tubulin Antibody (AA2): sc-80011

β Tubulin Antibody (AA2) is a mouse monoclonal IgG1 kappa light chain antibody designed to recognize β Tubulin, a critical structural protein within the cytoskeleton of eukaryotic cells. β Tubulin, also referred to as tubulin beta-1 chain or TUBB, pairs with α Tubulin to form heterodimers that polymerize into microtubule filaments, essential for maintaining cell shape, enabling intracellular transport, and facilitating cell division. The structural integrity and dynamic instability of microtubules, governed by the assembly and disassembly of these heterodimers, are fundamental for processes such as mitosis, vesicle trafficking, and neuronal function. Anti-β Tubulin antibody (AA2) targets the amino acids 412-430 region of β Tubulin derived from bovine brain tissue. β Tubulin (AA2) antibody exhibits broad species reactivity, effectively recognizing β Tubulin in mouse, rat, human, and bovine samples, and is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP) applications. By binding to a critical structural epitope, β Tubulin monoclonal antibody (AA2) facilitates accurate visualization and quantification of β Tubulin, enabling researchers to investigate microtubule dynamics and cytoskeletal organization under various physiological and pathological conditions. Anti-β Tubulin antibody (AA2) has proven invaluable for studies in cell biology, neurobiology, and cancer research through detection of multiple β Tubulin isoforms across different species.

The preferred beta Tubulin antibody is beta Tubulin Antibody (D-10): sc-5274.