beta-catenin Antibody (C-1F12): sc-69763
- beta-catenin Antibody (C-1F12) is a mouse monoclonal IgG2a provided at 100 µl
- raised against the His-tagged recombinant C-terminal fragment of β-catenin of human origin
- recommended for detection of β-catenin of mouse, rat and human origin by WB, IP and ELISA
- See beta-catenin (E-5): sc-7963 for beta-catenin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for beta-catenin Antibody (C-1F12). This work is in progress.
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SEE ALSO...
β-catenin Antibody (C-1F12) is a mouse monoclonal IgG2a antibody raised against the His-tagged recombinant C-terminal fragment of human β-catenin, also known as catenin beta-1. β-catenin is a multifunctional protein critical for cellular adhesion and signaling, linking E-cadherin to the actin cytoskeleton at adherens junctions to maintain tissue structure and integrity. The role of β-catenin in cell–cell adhesion is vital for ensuring proper tissue architecture, while its participation in the Wnt signaling pathway underlines its importance in regulating gene transcription for cell proliferation, differentiation, and development. β-catenin interacts with various proteins, including the tumor suppressor APC, and acts as a coactivator for transcription factors upon translocation to the nucleus, driving the expression of genes associated with growth and survival. Dysregulation of β-catenin function or signaling is implicated in numerous diseases, making β-catenin a focus of extensive research. Anti-β-catenin antibody (C-1F12) is validated for western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA), and reacts with β-catenin from human, mouse, and rat origins, offering broad application across species. β-catenin monoclonal antibody (C-1F12) provides a reliable tool for studying β-catenin′s roles in adhesion and signaling, advancing understanding of its functions in normal and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
beta-catenin Antibody (C-1F12) | sc-69763 | 100 µl | $322.00 |