β-Amyloid Antibody (20.1): sc-53822
- β-Amyloid Antibody (20.1) is a mouse monoclonal IgG2b κ, cited in 15 publications, provided at 200 µg/ml
- raised against amino acids 1-40 of β-Amyloid of human origin
- beta-Amyloid Antibody (20.1) is recommended for detection of APP and β-Amyloid of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-beta-Amyloid Antibody (20.1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for β-Amyloid Antibody (20.1) for WB and IHC(P) applications. This reagent is now offered in a bundle with β-Amyloid Antibody (20.1) (see ordering information below).
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β-Amyloid Antibody (20.1) is a mouse monoclonal IgG2b kappa light chain antibody that detects β-Amyloid of human origin through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). β-Amyloid (20.1) antibody is available in non-conjugated form and various conjugates, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® options. β-Amyloid, produced through proteolytic cleavage of amyloid precursor protein (APP), is crucial in Alzheimer′s disease pathogenesis, forming neurotoxic plaques in the brain. β-Amyloid (20.1) monoclonal antibody recognizes a protein significant in neurodegenerative diseases and metabolic disorders, with amyloid deposits linked to type II diabetes and Down syndrome. β-Amyloid presence in human platelets highlights broader physiological and pathological roles. APP undergoes alternative splicing to produce various isoforms, adding complexity to function and regulation. The 4 kDa β-Amyloid peptide formation contributes to neurofibrillary tangles and senile plaques development in Alzheimer′s disease. Interactions with structurally similar proteins like APLP1 and APLP2 demonstrate complex protein networks influencing amyloid-related conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-Amyloid Antibody (20.1) | sc-53822 | 200 µg/ml | $322.00 | |||
β-Amyloid Antibody (20.1): m-IgG Fc BP-HRP Bundle | sc-525618 | 200 µg Ab; 10 µg BP | $361.00 | |||
β-Amyloid Antibody (20.1) AC | sc-53822 AC | 500 µg/ml, 25% agarose | $424.00 | |||
β-Amyloid Antibody (20.1) HRP | sc-53822 HRP | 200 µg/ml | $322.00 | |||
β-Amyloid Antibody (20.1) FITC | sc-53822 FITC | 200 µg/ml | $336.00 | |||
β-Amyloid Antibody (20.1) PE | sc-53822 PE | 200 µg/ml | $349.00 | |||
β-Amyloid Antibody (20.1) Alexa Fluor® 488 | sc-53822 AF488 | 200 µg/ml | $364.00 | |||
β-Amyloid Antibody (20.1) Alexa Fluor® 546 | sc-53822 AF546 | 200 µg/ml | $364.00 | |||
β-Amyloid Antibody (20.1) Alexa Fluor® 594 | sc-53822 AF594 | 200 µg/ml | $364.00 | |||
β-Amyloid Antibody (20.1) Alexa Fluor® 647 | sc-53822 AF647 | 200 µg/ml | $364.00 | |||
β-Amyloid Antibody (20.1) Alexa Fluor® 680 | sc-53822 AF680 | 200 µg/ml | $364.00 | |||
β-Amyloid Antibody (20.1) Alexa Fluor® 790 | sc-53822 AF790 | 200 µg/ml | $364.00 |