Date published: 2026-6-30
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beta 2 Adrenergic Receptor/ADRB2/β2-AR Antibody (E-3) - Western Blotting - Image 379893SAM Transcription Activation: SAM system utilizing dCas9-VP64, MS2-P65-HSF1, and sgRNA for precise gene transcription activation.
β2-AR Antibody (E-3): sc-271322. Western blot analysis of β2-AR expression in HUV-EC-C whole cell lysate.

Not CRISPR data: the image illustrates antibody quality for visualizing CRISPR experiment results.
β2-AR Antibody (E-3): sc-271322. Western blot analysis of β2-AR expression in HUV-EC-C whole cell lysate.

Not CRISPR data: the image illustrates antibody quality for visualizing CRISPR experiment results.

beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h): sc-400291-ACT

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Datasheets
  • Target species: human
  • 20 µg of transfection-ready, purified plasmid DNA; Suitable for up to 20 transfections
  • beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h) is a synergistic activation mediator (SAM) transcription activation system designed to specifically upregulate gene expression
  • beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h) consists of three plasmids at a 1:1:1 mass ratio: a plasmid encoding the deactivated Cas9 (dCas9) nuclease (D10A and N863A) fused to the transactivation domain VP64, and a blasticidin resistance gene; a plasmid encoding the MS2-p65-HSF1 fusion protein, and a hygromycin resistance gene; a plasmid encoding a target-specific 20 nt guide RNA fused to two MS2 RNA aptamers, and a puromycin resistance gene
  • The resulting SAM complex binds to a site-specific region approximately 200-250 nt upstream of the transcriptional start site and provides robust recruitment of transcription factors for highly efficient gene activation
  • gRNAs encoded by beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h) and beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h2) target distinct regulatory regions upstream of the ADRB2 transcriptional start site. One or both designs may be available
  • Following transfection, gene knockout efficiency can be assayed by WB, IF or IHC using antibody: beta 2 Adrenergic Receptor/ADRB2/β2-AR Antibody (E-3): sc-271322
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    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h)

    sc-400291-ACT
    20 µg
    		$397.00

    beta 2 Adrenergic Receptor/ADRB2/β2-AR CRISPR Activation Plasmid (h2)

    sc-400291-ACT-2
    20 µg
    		$397.00
    1-800-457-3801
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