BDV Antibody (VPM22): sc-101591
- BDV Antibody (VPM22) is a mouse monoclonal IgG2b BDV antibody provided at 200 µg/ml
- raised against a lysate of ovine cells infected with the cytopathic isolate of BDV
- BDV Antibody (VPM22) is recommended for detection of the p125/p80 non-structural region of Border Disease Virus by IP and ELISA
- Anti-BDV Antibody (VPM22) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BDV Antibody (VPM22). This work is in progress.
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BDV Antibody (VPM22) is a mouse monoclonal IgG2b antibody that detects the BDV protein of NSR and Pestiviruses origin by immunoprecipitation (IP) and enzyme-linked immunosorbent assay (ELISA). Anti-BDV antibody (VPM22) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Pestiviruses, including Border disease virus (BDV), are enveloped single-stranded RNA viruses that play a significant role in veterinary medicine due to their impact on livestock health. BDV is particularly notorious for causing congenital diseases in sheep, with its two forms—cytopathic (CP) and non-cytopathic (NCP)—resulting in different pathological outcomes. The NCP form is especially concerning during the first half of gestation, as this variant can lead to severe syndromes such as early embryonic death, abortion, stillbirth, and the birth of lambs with malformations or reduced vitality. Understanding the structure of BDV protein is crucial, as this component influences viral evasion of host immune response and establishment of infection. BDV protein′s envelope glycoproteins play a key role in receptor binding and fusion, which are essential for viral entry into host cells. Using BDV (VPM22) monoclonal antibody in research helps scientists gain insights into the mechanisms of BDV pathogenesis and develop strategies for disease control and prevention in affected livestock populations.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BDV Antibody (VPM22) References:
- Border disease of sheep: the disease in the newborn, adolescent and adult. | Sawyer, MM. 1992. Comp Immunol Microbiol Infect Dis. 15: 171-7. PMID: 1325332
- [Asymptomatic carriage of Pestivirus in ruminants]. | Pastoret, PP., et al. 1992. Rev Sci Tech. 11: 1087-96. PMID: 1339065
- Cytopathic and non-cytopathic biotypes of border disease virus induce polypeptides of different molecular weight with common antigenic determinants. | Dutia, BM., et al. 1990. J Gen Virol. 71 (Pt 5): 1227-32. PMID: 1693167
- Ruminant pestiviruses. | Nettleton, PF. and Entrican, G. 1995. Br Vet J. 151: 615-42. PMID: 8605577
- Border disease of sheep--aspects for diagnostic and epidemiologic consideration. | Sawyer, MM., et al. 1991. Arch Virol Suppl. 3: 97-100. PMID: 9210930
- Border disease of sheep and goats. | Nettleton, PF., et al. 1998. Vet Res. 29: 327-40. PMID: 9689745
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BDV Antibody (VPM22) | sc-101591 | 200 µg/ml | $316.00 | |||
BDV Antibody (VPM22) AC | sc-101591 AC | 500 µg/ml, 25% agarose | $416.00 | |||
BDV Antibody (VPM22) HRP | sc-101591 HRP | 200 µg/ml | $316.00 | |||
BDV Antibody (VPM22) FITC | sc-101591 FITC | 200 µg/ml | $330.00 | |||
BDV Antibody (VPM22) PE | sc-101591 PE | 200 µg/ml | $343.00 | |||
BDV Antibody (VPM22) Alexa Fluor® 488 | sc-101591 AF488 | 200 µg/ml | $357.00 | |||
BDV Antibody (VPM22) Alexa Fluor® 546 | sc-101591 AF546 | 200 µg/ml | $357.00 | |||
BDV Antibody (VPM22) Alexa Fluor® 594 | sc-101591 AF594 | 200 µg/ml | $357.00 | |||
BDV Antibody (VPM22) Alexa Fluor® 647 | sc-101591 AF647 | 200 µg/ml | $357.00 | |||
BDV Antibody (VPM22) Alexa Fluor® 680 | sc-101591 AF680 | 200 µg/ml | $357.00 | |||
BDV Antibody (VPM22) Alexa Fluor® 790 | sc-101591 AF790 | 200 µg/ml | $357.00 |