Bcl-G Antibody (QQ2): sc-101218

Bcl-G Antibody (QQ2) is a mouse monoclonal IgG1 antibody that detects Bcl-G in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Bcl-G, also known as BCL2L14 or BCLG, is a 327 amino acid cytoplasmic protein that plays a crucial role in regulating apoptosis, a process essential for maintaining tissue homeostasis and protecting against diseases, including cancer. Anti-Bcl-G antibody (QQ2) recognizes a protein that belongs to the Bcl-2 family, known for involvement in apoptotic signaling pathways. Bcl-G is expressed in three alternatively spliced isoforms: short, medium, and long, with the short isoform being testis-specific and localized to cytosolic organelles, while the long isoform is more widely distributed throughout the cytosol. The structural diversity of these isoforms allows for differential regulation of apoptosis in various tissues, highlighting Bcl-G′s importance in both normal physiological processes and pathological conditions. Notably, overexpression of Bcl-G has been linked to the induction of apoptosis in cells, suggesting a potential role in tumor suppression and making Bcl-G a valuable target for therapeutic interventions in cancer treatment. Bcl-G monoclonal antibody (QQ2) serves as an essential tool for researchers studying apoptosis mechanisms and Bcl-G′s implications in various diseases.

The preferred Bcl-G antibody is Bcl-G Antibody (E-10): sc-398223.