Bcl-G Antibody (E-10): sc-398223
- Bcl-G Antibody (E-10) is a mouse monoclonal IgG1 κ Bcl-G antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of Bcl-G of human origin
- Bcl-G Antibody (E-10) is recommended for detection of Bcl-G of human origin by WB, IP, IF and ELISA
- Anti-Bcl-G Antibody (E-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Bcl-G Antibody (E-10) for WB applications. These reagents are now offered in bundles with Bcl-G Antibody (E-10) (see ordering information below).
QUICK LINKS
SEE ALSO...
Bcl-G Antibody (E-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects Bcl-G protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Bcl-G monoclonal antibody (E-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Bcl-G, also known as BCL2L14 or BCLG, is a 327 amino acid cytoplasmic protein that plays a crucial role in regulating apoptosis, a process essential for maintaining cellular homeostasis and eliminating damaged or unwanted cells. Bcl-G belongs to the Bcl-2 family, known for involvement in apoptotic signaling pathways. Bcl-G is expressed in three alternatively spliced isoforms: short, medium, and long, with the short isoform being testis-specific and localized to cytosolic organelles, while the long isoform is more widely distributed throughout the cytosol. Bcl-G′s ability to induce apoptosis upon overexpression highlights a potential role in tumor suppression, making Bcl-G a significant target for research in cancer biology. Understanding Bcl-G function and regulation is vital for developing therapeutic strategies aimed at modulating apoptosis in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Bcl-G Antibody (E-10) References:
- Bcl-G, a novel pro-apoptotic member of the Bcl-2 family. | Guo, B., et al. 2001. J Biol Chem. 276: 2780-5. PMID: 11054413
- Bcl-2 expression in preinvasive and invasive cervical lesions. | Ozalp, SS., et al. 2002. Eur J Gynaecol Oncol. 23: 419-22. PMID: 12440815
- BH3 domain mutation of proapoptotic genes Bad, Bmf and Bcl-G is rare in transitional cell carcinomas of the urinary bladder. | Soung, YH., et al. 2006. Pathology. 38: 33-4. PMID: 16484005
- The ubiquitin-like protein MNSFbeta regulates ERK-MAPK cascade. | Nakamura, M. and Yamaguchi, S. 2006. J Biol Chem. 281: 16861-16869. PMID: 16621790
- A novel TEL-AML1 fusion transcript involving the pro-apoptotic gene BCL-G in pediatric precursor B acute lymphoblastic leukemia. | Abdelhaleem, M., et al. 2006. Leukemia. 20: 1294. PMID: 16673018
- Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family. | Lin, ML., et al. 2007. Breast Cancer Res. 9: R17. PMID: 17280616
- Mutational analysis of the BH3 domains of proapoptotic Bcl-2 family genes Bad, Bmf and Bcl-G in laryngeal squamous cell carcinomas. | Yoo, NJ., et al. 2007. Tumori. 93: 195-7. PMID: 17557568
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bcl-G Antibody (E-10) | sc-398223 | 200 µg/ml | $322.00 | |||
Bcl-G Antibody (E-10): m-IgG Fc BP-HRP Bundle | sc-527752 | 200 µg Ab; 10 µg BP | $361.00 | |||
Bcl-G Antibody (E-10): m-IgG1 BP-HRP Bundle | sc-533125 | 200 µg Ab; 20 µg BP | $361.00 | |||
Bcl-G Antibody (E-10) AC | sc-398223 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Bcl-G Antibody (E-10) HRP | sc-398223 HRP | 200 µg/ml | $322.00 | |||
Bcl-G Antibody (E-10) FITC | sc-398223 FITC | 200 µg/ml | $336.00 | |||
Bcl-G Antibody (E-10) PE | sc-398223 PE | 200 µg/ml | $349.00 | |||
Bcl-G Antibody (E-10) Alexa Fluor® 488 | sc-398223 AF488 | 200 µg/ml | $364.00 | |||
Bcl-G Antibody (E-10) Alexa Fluor® 546 | sc-398223 AF546 | 200 µg/ml | $364.00 | |||
Bcl-G Antibody (E-10) Alexa Fluor® 594 | sc-398223 AF594 | 200 µg/ml | $364.00 | |||
Bcl-G Antibody (E-10) Alexa Fluor® 647 | sc-398223 AF647 | 200 µg/ml | $364.00 | |||
Bcl-G Antibody (E-10) Alexa Fluor® 680 | sc-398223 AF680 | 200 µg/ml | $364.00 | |||
Bcl-G Antibody (E-10) Alexa Fluor® 790 | sc-398223 AF790 | 200 µg/ml | $364.00 |