BBS4 Antibody (1292CT845.130.218): sc-517315

BBS4 Antibody (1292CT845.130.218) is a mouse monoclonal IgG1 antibody that detects BBS4 protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-BBS4 antibody (1292CT845.130.218) is available as a non-conjugated format. BBS4 plays a crucial role in the function of cilia, which are essential for various cellular processes, including signaling pathways and the maintenance of cellular homeostasis. Specifically, BBS4 is involved in the assembly and stability of the basal body and ciliary structures, which are vital for proper sensory function and development. Defects in BBS4 can lead to Bardet-Biedl syndrome, a complex genetic disorder characterized by a range of symptoms such as obesity, photoreceptor degeneration, and renal abnormalities. The importance of BBS4 in ciliary function underscores its potential as a target for therapeutic interventions aimed at addressing the underlying causes of ciliary dysfunction. With its ability to interact with key components of the dynein transport machinery, BBS4 is integral to the recruitment of proteins necessary for ciliary assembly and maintenance, making BBS4 a significant focus of research in understanding ciliary-related diseases.

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BBS4 Antibody (1292CT845.130.218) References:

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