BAT2L Antibody (D-2): sc-393604
- BAT2L Antibody (D-2) is a mouse monoclonal IgG1 κ BAT2L antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2102-2139 within an internal region of BAT2L of human origin
- BAT2L Antibody (D-2) is recommended for detection of BAT2L of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and porcine
- Anti-BAT2L Antibody (D-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for BAT2L Antibody (D-2) for WB applications. These reagents are now offered in bundles with BAT2L Antibody (D-2) (see ordering information below).
BAT2L Antibody (D-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects BAT2L of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BAT2L Antibody (D-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BAT2L, also known as HLA-B-associated transcript 2-like 1 or KIAA0515, is a 1,535 amino acid protein that exists in four isoforms due to alternative splicing. BAT2L plays a crucial role in the immune response by influencing the expression of major histocompatibility complex (MHC) molecules, which are essential for the presentation of antigens to T cells. Proper functioning of BAT2L is vital for effective immune surveillance and response, as BAT2L helps distinguish between self and non-self, thereby preventing autoimmune reactions and enhancing the ability to combat infections. The gene encoding BAT2L is located on human chromosome 9, a region significant for gender determination and association with various genetic disorders, including hereditary hemorrhagic telangiectasia and familial dysautonomia. Understanding BAT2L function and importance can provide insights into potential implications in immunological research and therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BAT2L Antibody (D-2) References:
- DNA sequence and analysis of human chromosome 9. | Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
- BCR-ABL activates STAT3 via JAK and MEK pathways in human cells. | Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
- BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. | Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
- Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia. | Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
- Phenotypic and cytogenetic spectrum of 9p trisomy. | Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
- Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia. | Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
- Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease). | Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
- A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. | Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
- Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia. | Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
- RNA binding protein PRRC2B mediates translation of specific mRNAs and regulates cell cycle progression. | Jiang, F., et al. 2023. Nucleic Acids Res. 51: 5831-5846. PMID: 37125639
- The Role of PRRC2B in Cerebral Vascular Remodeling Under Acute Hypoxia in Mice. | Li, S., et al. 2023. Adv Sci (Weinh). 10: e2300892. PMID: 37395402
- PRRC2B modulates oligodendrocyte progenitor cell development and myelination by stabilizing Sox2 mRNA. | Zhang, Y., et al. 2024. Cell Rep. 43: 113930. PMID: 38507412
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAT2L Antibody (D-2) | sc-393604 | 200 µg/ml | $322.00 | |||
BAT2L Antibody (D-2): m-IgG Fc BP-HRP Bundle | sc-527696 | 200 µg Ab; 10 µg BP | $361.00 | |||
BAT2L Antibody (D-2): m-IgG1 BP-HRP Bundle | sc-533069 | 200 µg Ab; 20 µg BP | $361.00 | |||
BAT2L Antibody (D-2) AC | sc-393604 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BAT2L Antibody (D-2) HRP | sc-393604 HRP | 200 µg/ml | $322.00 | |||
BAT2L Antibody (D-2) FITC | sc-393604 FITC | 200 µg/ml | $336.00 | |||
BAT2L Antibody (D-2) PE | sc-393604 PE | 200 µg/ml | $349.00 | |||
BAT2L Antibody (D-2) Alexa Fluor® 488 | sc-393604 AF488 | 200 µg/ml | $364.00 | |||
BAT2L Antibody (D-2) Alexa Fluor® 546 | sc-393604 AF546 | 200 µg/ml | $364.00 | |||
BAT2L Antibody (D-2) Alexa Fluor® 594 | sc-393604 AF594 | 200 µg/ml | $364.00 | |||
BAT2L Antibody (D-2) Alexa Fluor® 647 | sc-393604 AF647 | 200 µg/ml | $364.00 | |||
BAT2L Antibody (D-2) Alexa Fluor® 680 | sc-393604 AF680 | 200 µg/ml | $364.00 | |||
BAT2L Antibody (D-2) Alexa Fluor® 790 | sc-393604 AF790 | 200 µg/ml | $364.00 | |||
BAT2L (D-2) Neutralizing Peptide | sc-393604 P | 100 µg/0.5 ml | $69.00 |