B7-1 Antibody (2Q1684): sc-70393

B7-1 Antibody (2Q1684) is an Arm. hamster IgG antibody that detects B7-1 in mouse, rat, and canine species by flow cytometry (FCM). B7-1, also known as CD80, plays a crucial role in the immune response by providing essential costimulatory signals necessary for T cell activation and proliferation. B7-1 is primarily located on the surface of antigen-presenting cells, where B7-1 interacts with the receptors CTLA-4 and CD28 on T cells, thereby influencing the balance between immune activation and inhibition. This interaction is vital for maintaining immune homeostasis and preventing autoimmunity, as B7-1 helps regulate T cell responses to antigens. The ability of B7-1 to modulate T cell activity underscores its importance in both adaptive immunity and potential therapeutic applications, such as in cancer immunotherapy, where enhancing T cell responses can improve treatment outcomes. Anti-B7-1 antibody (2Q1684) is an invaluable tool for researchers studying T cell dynamics and the intricate signaling pathways involved in immune regulation.

The preferred B7-1 antibody is B7-1 Antibody (F-7): sc-376012.