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ATP5E Antibody (Z88) is a mouse monoclonal IgG1 antibody that detects mitochondrial ATPase ε chain (ATP5E) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ATP5E plays a crucial role in cellular energy metabolism by catalyzing the synthesis of adenosine triphosphate (ATP) within mitochondria, which is essential for powering numerous biochemical processes in cells. ATP5E is located in the inner mitochondrial membrane, where ATP5E forms part of the ATP synthase complex, a vital component that converts the electrochemical gradient generated by the electron transport chain into chemical energy stored in ATP. This localization is significant because ATP5E efficiently harnesses the proton motive force created during cellular respiration, thereby ensuring cells have a continuous supply of ATP to meet energy demands. The structure of ATP5E, which includes a small ε chain composed of 50 amino acids, is integral to the overall function of the ATP synthase complex, as ATP5E helps stabilize the interaction between the F1 catalytic core and the F0 membrane channel, facilitating effective ATP production. Anti-ATP5E antibody (Z88) is an invaluable tool for researchers studying mitochondrial function and energy metabolism in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ATP5E Antibody (Z88) | sc-81874 | 100 µg/ml | $333.00 |