ART3 Antibody (G-10): sc-515157

ART3 Antibody (G-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects ART3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ART3 (G-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ART3, also known as Ecto-ADP-ribosyltransferase 3, is primarily localized in the testis and specifically expressed in spermatocytes, highlighting a potential role in spermatogenesis. Although ART3 does not exhibit ADP-ribosyltransferase activity due to the absence of the R-S-EXE active site motif, ART3′s presence in testicular tissues suggests involvement in regulating cellular processes during sperm development. Understanding ART3 localization and function is crucial, as research may provide insights into male fertility and mechanisms underlying spermatogenesis, making anti-ART3 antibody (G-10) an essential tool for researchers studying reproductive biology and related fields.

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ART3 Antibody (G-10) References:

1. Characterization of glycosylphosphatidylinositiol-anchored, secreted, and intracellular vertebrate mono-ADP-ribosyltransferases.  |  Okazaki, IJ. and Moss, J. 1999. Annu Rev Nutr. 19: 485-509. PMID: 10448534
2. Use of genetic immunization to raise antibodies recognizing toxin-related cell surface ADP-ribosyltransferases in native conformation.  |  Koch-Nolte, F., et al. 2005. Cell Immunol. 236: 66-71. PMID: 16271711
3. Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes.  |  Friedrich, M., et al. 2006. Asian J Androl. 8: 281-7. PMID: 16625277
4. Genomic organization and expression of the human mono-ADP-ribosyltransferase ART3 gene.  |  Friedrich, M., et al. 2006. Biochim Biophys Acta. 1759: 270-80. PMID: 16934346
5. Identification of corticosteroid-regulated genes in cardiomyocytes by serial analysis of gene expression.  |  Muller, O., et al. 2007. Genomics. 89: 370-7. PMID: 17174066
6. Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility.  |  Okada, H., et al. 2008. PLoS Genet. 4: e26. PMID: 18266473
7. Immunological and structural conservation of mammalian skeletal muscle glycosylphosphatidylinositol-linked ADP-ribosyltransferases.  |  Okazaki, IJ., et al. 1994. Biochemistry. 33: 12828-36. PMID: 7947688
8. Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins.  |  Koch-Nolte, F., et al. 1997. Genomics. 39: 370-6. PMID: 9119374
9. Molecular characterization and expression of the gene for mouse NAD+:arginine ecto-mono(ADP-ribosyl)transferase, Art1.  |  Braren, R., et al. 1998. Biochem J. 336 (Pt 3): 561-8. PMID: 9841866

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ART3 Antibody (G-10) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-ART3 Antibody (G-10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ART3 Antibody (G-10) Specifications

Alternate Product Name: ART3

Product Clone Name: G-10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-300

Epitope Target: ART3

Epitope Species: human

Product Reactivity/Detection: ART3

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for ART3 Antibody (G-10): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin