Arp3 Antibody (A-10): sc-376625
- Arp3 Antibody (A-10) is a mouse monoclonal IgG2b κ Arp3 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 41-77 near the N-terminus of Arp3 of Saccharomyces cerevisiae origin
- Arp3 Antibody (A-10) is recommended for detection of Arp3 of y origin by WB, IP, IF and ELISA
- Anti-Arp3 Antibody (A-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Arp3 Antibody (A-10). This work is in progress.
Arp3 Antibody (A-10) is a mouse monoclonal IgG2b kappa light chain antibody that detects the Arp3 protein of Saccharomyces cerevisiae origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Arp3 (A-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The Arp3 protein plays a crucial role in actin polymerization, which is essential for numerous cellular functions such as chemotaxis, cell migration, cell adhesion, and platelet activation. Actin polymerization is initiated through the Arp2/3 complex, which includes Arp2 and Arp3, along with several accessory proteins. This complex is vital for nucleating new actin filaments and facilitating the branching of existing filaments into a dense network, thereby enabling dynamic restructuring of the cytoskeleton. The Arp2/3 complex binds to the pointed end of actin filaments or associates with the sides of existing filaments, promoting growth in the barbed direction. Additionally, Arp2/3 complex activity is regulated by the Rho family of small GTPases, particularly Cdc42, which activates the complex through interaction with WASP proteins, leading to the formation of lamellipodia and filopodia. This intricate regulation underscores Arp3′s importance in maintaining cellular architecture and facilitating movement, making anti-Arp3 antibody (A-10) an invaluable tool for researchers studying cytoskeletal dynamics and related cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Arp3 Antibody (A-10) | sc-376625 | 200 µg/ml | $316.00 | |||
Arp3 Antibody (A-10) AC | sc-376625 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Arp3 Antibody (A-10) HRP | sc-376625 HRP | 200 µg/ml | $316.00 | |||
Arp3 Antibody (A-10) FITC | sc-376625 FITC | 200 µg/ml | $330.00 | |||
Arp3 Antibody (A-10) PE | sc-376625 PE | 200 µg/ml | $343.00 | |||
Arp3 Antibody (A-10) Alexa Fluor® 488 | sc-376625 AF488 | 200 µg/ml | $357.00 | |||
Arp3 Antibody (A-10) Alexa Fluor® 546 | sc-376625 AF546 | 200 µg/ml | $357.00 | |||
Arp3 Antibody (A-10) Alexa Fluor® 594 | sc-376625 AF594 | 200 µg/ml | $357.00 | |||
Arp3 Antibody (A-10) Alexa Fluor® 647 | sc-376625 AF647 | 200 µg/ml | $357.00 | |||
Arp3 Antibody (A-10) Alexa Fluor® 680 | sc-376625 AF680 | 200 µg/ml | $357.00 | |||
Arp3 Antibody (A-10) Alexa Fluor® 790 | sc-376625 AF790 | 200 µg/ml | $357.00 | |||
Arp3 (A-10) Neutralizing Peptide | sc-376625 P | 100 µg/0.5 ml | $68.00 |