Arp2 Antibody (E-2): sc-137250

Arp2 Antibody (E-2) is a mouse monoclonal IgG1 antibody that detects Arp2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Arp2 is a crucial component of the Arp2/3 complex, which plays a vital role in actin polymerization, a process essential for various cellular functions including cell migration, adhesion, and the formation of cellular structures. The Arp2/3 complex facilitates the nucleation of new actin filaments, enabling the rapid reorganization of the actin cytoskeleton in response to extracellular signals. This dynamic regulation is particularly important in processes such as chemotaxis, where cells must move toward chemical signals, and in the formation of cellular protrusions like lamellipodia and filopodia, which are critical for cell movement and interaction with the environment. By binding to the pointed end of existing actin filaments or associating with their sides, the Arp2/3 complex promotes the growth of new filaments in a branched network, thereby enhancing the cell′s ability to adapt and respond to its surroundings. Anti-Arp2 antibody (E-2) is an invaluable tool for researchers studying the intricate mechanisms of actin dynamics and their implications in cellular behavior and disease.

The preferred Arp2 antibody is Arp2 Antibody (E-12): sc-166103.