ARMCX1 Antibody (G-5): sc-376291

ARMCX1 Antibody (G-5) is a mouse monoclonal IgM antibody that detects ARMCX1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-ARMCX1 antibody (G-5) is available as the non-conjugated form. ARMCX1, also known as armadillo repeat containing, X-linked 1, is a 453 amino acid single-pass membrane protein that plays a crucial role in various cellular processes, including cell migration, proliferation, and tissue maintenance, which are vital for normal physiological functions and the prevention of tumorigenesis. ARMCX1 is predominantly expressed in the ovary, heart, testis, prostate, brain, spleen, and colon, while showing minimal expression in the liver and thymus. ARMCX1 contains three armadillo repeats, which are essential for structural integrity and function in signal transduction pathways. ARMCX1 has been implicated in tumor suppression, as ARMCX1 is significantly down-regulated in several human carcinomas, including lung, prostate, colon, pancreas, and ovarian cancers, highlighting potential as a biomarker for cancer diagnosis and therapy.

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ARMCX1 Antibody (G-5) References:

1. ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas.  |  Kurochkin, IV., et al. 2001. Biochem Biophys Res Commun. 280: 340-7. PMID: 11162520
2. DNA microarray analysis of region-specific gene expression in the mouse epididymis.  |  Hsia, N. and Cornwall, GA. 2004. Biol Reprod. 70: 448-57. PMID: 14561649
3. Temporal and spatial expression profile of the novel armadillo-related gene, Alex2, during testicular differentiation in the mouse embryo.  |  Smith, CA., et al. 2005. Dev Dyn. 233: 188-93. PMID: 15759267
4. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.  |  Olsen, JV., et al. 2006. Cell. 127: 635-48. PMID: 17081983
5. Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1.  |  Rohrbeck, A. and Borlak, J. 2009. PLoS One. 4: e7315. PMID: 19812696
6. Roles of Armadillo, a Drosophila catenin, during central nervous system development.  |  Loureiro, J. and Peifer, M. 1998. Curr Biol. 8: 622-32. PMID: 9635189
7. The armadillo family of structural proteins.  |  Hatzfeld, M. 1999. Int Rev Cytol. 186: 179-224. PMID: 9770300

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ARMCX1 Antibody (G-5) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ARMCX1 Antibody (G-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ARMCX1 Antibody (G-5) Specifications

Alternate Product Name: ARMCX1

Product Clone Name: G-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 203-233

Epitope Target: ARMCX1

Epitope Species: human

Product Reactivity/Detection: ARMCX1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ARMCX1 Antibody (G-5): P: Blocking Peptide