ARL1 Antibody (B-2): sc-393785

ARL1 Antibody (B-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARL1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARL1 (B-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARL1, a member of the ADP-ribosylation factor-like (ARL) subfamily of small GTPases, plays a crucial role in regulating membrane traffic and maintaining the structure and function of the Golgi apparatus. ARL1 is primarily localized to the trans side of the Golgi, where ARL1 is involved in vesicular transport processes essential for both exocytosis and endocytosis. Proper functioning of ARL1 is vital for cellular homeostasis, as ARL1 influences the transport of proteins and lipids, thereby impacting various cellular functions. Additionally, ARL1′s interaction with other proteins, such as those involved in the Golgi′s structural integrity, underscores ARL1′s importance in cellular signaling and transport mechanisms. Understanding ARL1′s role and interactions can provide insights into molecular pathways that govern cellular organization and function, making anti-ARL1 antibody (B-2) an invaluable tool for researchers studying these processes.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

ARL1 Antibody (B-2) References:

1. Regulation of Golgi structure and function by ARF-like protein 1 (Arl1).  |  Lu, L., et al. 2001. J Cell Sci. 114: 4543-55. PMID: 11792819
2. An ARL1 mutation affected autophagic cell death in yeast, causing a defect in central vacuole formation.  |  Abudugupur, A., et al. 2002. Cell Death Differ. 9: 158-68. PMID: 11840166
3. ARL1 and membrane traffic in Saccharomyces cerevisiae.  |  Rosenwald, AG., et al. 2002. Yeast. 19: 1039-56. PMID: 12210899
4. The mammalian ARF-like protein 1 (Arl1) is associated with the Golgi complex.  |  Lowe, SL., et al. 1996. J Cell Sci. 109 (Pt 1): 209-20. PMID: 8834805
5. Characterization of an ADP-ribosylation factor-like 1 protein in Saccharomyces cerevisiae.  |  Lee, FJ., et al. 1997. J Biol Chem. 272: 30998-1005. PMID: 9388248

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ARL1 Antibody (B-2) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-ARL1 Antibody (B-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ARL1 Antibody (B-2) Specifications

Alternate Product Name: ARL1

Product Clone Name: B-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 128-181

Epitope Target: ARL1

Epitope Species: human

Product Reactivity/Detection: ARL1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for ARL1 Antibody (B-2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin