ARIH1 Antibody (B-2): sc-390763
- ARIH1 Antibody (B-2) is a mouse monoclonal IgM κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 532-557 of ARIH1 of human origin
- recommended for detection of ARIH1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ARIH1 Antibody (B-2). This work is in progress.
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SEE ALSO...
ARIH1 Antibody (B-2) is a mouse monoclonal IgM antibody that detects ARIH1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ARIH1, also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI, MOP-6, or UBCH7BP, is a 557 amino acid cytoplasmic protein that plays a crucial role in the regulation of protein degradation and translation. ARIH1 is characterized by the presence of two RING-type zinc fingers and one in-between RING fingers (IBR) domain, which are essential for its function as an E3 ubiquitin-protein ligase. ARIH1 interacts with UBCH7, facilitating the transfer of ubiquitin to specific substrates, thereby marking them for proteasomal degradation. ARIH1 polyubiquitylates eIF4E2, a key regulator of translation, which underscores its significance in controlling protein synthesis and maintaining cellular homeostasis. ARIH1′s ability to modulate eIF4E2 levels highlights its potential impact on various cellular processes, including stress responses and cell proliferation, making anti-ARIH1 antibody (B-2) a valuable tool for researchers studying these critical biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARIH1 Antibody (B-2) | sc-390763 | 200 µg/ml | $316.00 | |||
ARIH1 (B-2) Neutralizing Peptide | sc-390763 P | 100 µg/0.5 ml | $68.00 |