ARID3A Antibody (ARIDE9C11): sc-81254
- ARID3A Antibody (ARIDE9C11) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the N-terminus of DRIL1 of human origin
- recommended for detection of ARID3A of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ARID3A Antibody (ARIDE9C11). This work is in progress.
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ARID3A Antibody (ARIDE9C11) is a mouse monoclonal IgG1 antibody that detects ARID3A in human samples through western blotting (WB) and immunoprecipitation (IP) applications. ARID3A, also known as DRIL1 in humans and Bright in mice, plays a crucial role as a transcriptional activator, influencing gene expression during development and cellular differentiation. Anti-ARID3A antibody (ARIDE9C11) recognizes a protein particularly important due to its involvement in the regulation of genes associated with cell proliferation and differentiation, especially in tissues such as the gut and salivary glands. The presence of an A/T-rich DNA-binding (ARID) domain allows ARID3A to interact with specific DNA sequences, facilitating the transcription of target genes. Additionally, ARID3A′s unique tetramerization domain enables formation of complexes that enhance regulatory capabilities. Notably, the gene encoding ARID3A is linked to Peutz-Jeghers syndrome, an autosomal-dominant disorder that increases the risk of gastrointestinal cancers, highlighting ARID3A′s significance in both normal physiology and disease states. Furthermore, ARID3A shares a carboxy terminal region with E2FBP1, a protein that regulates transcription factors involved in cell cycle control, underscoring the interconnectedness of these regulatory pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARID3A Antibody (ARIDE9C11) | sc-81254 | 100 µg/ml | $339.00 |