ARD Antibody (C-10): sc-374413
- ARD Antibody (C-10) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 34-171 mapping within an internal region of ARD of human origin
- recommended for detection of ARD of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for ARD Antibody (C-10) for WB applications. These reagents are now offered in bundles with ARD Antibody (C-10) (see ordering information below).
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ARD Antibody (C-10) is a mouse monoclonal IgG2a antibody that detects ARD (acireductone dioxygenase) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARD is a 179 amino acid protein that plays a vital role in the L-methionine biosynthetic pathway, catalyzing the conversion of (S)-methyl-5-thio-alpha-D-ribose 1-phosphate to L-methionine, a process essential for protein synthesis and cellular function. ARD (C-10) antibody recognizes a protein predominantly localized in the nucleus and the cytoplasmic side of the cell membrane, suggesting a dual role in both gene regulation and cellular signaling. ARD is expressed in various tissues, including the brain, heart, lung, colon, liver, kidney, spleen, and skeletal muscle, highlighting its importance in multiple physiological processes. Additionally, ARD interacts with membrane-type matrix metalloproteinase 1 (MT-MMP-1), potentially modulating cell migration, which is crucial in developmental and pathological contexts. Multiple isoforms of ARD exist due to alternative splicing, further underscoring the complexity of regulation and function, making anti-ARD antibody (C-10) an invaluable tool for researchers studying this multifaceted protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARD Antibody (C-10) | sc-374413 | 200 µg/ml | $322.00 | |||
ARD Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-540449 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARD Antibody (C-10): m-IgG2a BP-HRP Bundle | sc-546908 | 200 µg Ab; 10 µg BP | $361.00 |