ARALAR Antibody (8): sc-135840
- ARALAR Antibody (8) is a mouse monoclonal mouse IgG1 provided at 50 µg/0.5 ml
- raised against amino acids 1-119 of ARALAR of human origin
- recommended for detection of ARALAR of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ARALAR Antibody (8). This work is in progress.
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SEE ALSO...
ARALAR Antibody (8) is a mouse monoclonal IgG1 antibody that detects ARALAR in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). ARALAR, encoded by the SLC25A12 gene, plays a crucial role in calcium signaling within mitochondria, which is essential for the organelle′s response to various extracellular stimuli. ARALAR is primarily located in the inner mitochondrial membrane, where ARALAR facilitates the transport of aspartate and glutamate, thereby participating in the malate-aspartate NADH shuttle. ARALAR′s proper functioning is vital for synthesizing brain aspartate and N-acetylaspartate, both of which are important for neuronal health and myelin formation. Additionally, ARALAR′s ability to transmit small calcium signals to mitochondria through an increase in mitochondrial NADH is significant for maintaining cellular energy metabolism. Dysregulation of ARALAR has been linked to various neurological disorders, including schizophrenia, highlighting ARALAR′s importance in both normal physiology and disease states. Anti-ARALAR antibody (8) is an invaluable tool for researchers studying mitochondrial function and calcium signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARALAR Antibody (8) | sc-135840 | 50 µg/0.5 ml | $316.00 |