ARA160 Antibody (C-10): sc-398411
- ARA160 Antibody (C-10) is a mouse monoclonal IgG1 κ ARA160 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 811-1093 mapping at the C-terminus of ARA160 of human origin
- ARA160 Antibody (C-10) is recommended for detection of ARA160 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ARA160 Antibody (C-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ARA160 Antibody (C-10) for WB applications. These reagents are now offered in bundles with ARA160 Antibody (C-10) (see ordering information below).
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ARA160 Antibody (C-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARA160 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARA160 (C-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARA160 plays a crucial role in regulating androgen receptor (AR) activity, which is essential for male reproductive physiology and male characteristics development. ARA160 interacts with AR and modulates transcriptional activity, influencing gene expression critical for male reproductive function. This interaction holds particular importance as AR mediates effects of androgens like testosterone and dihydrotestosterone, vital for male development and health. ARA160′s association with chromatin remodeling complexes, such as the SNF/SWI complex, further emphasizes its significance in facilitating gene expression changes in response to hormonal signals. Using anti-ARA160 antibody (C-10) enables researchers to gain valuable insights into molecular mechanisms underlying androgen signaling and implications in male reproductive health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARA160 Antibody (C-10) References:
- Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor. | Kang, HY., et al. 1999. J Biol Chem. 274: 8570-6. PMID: 10085091
- Isolation and characterization of a novel human gene (HFB30) which encodes a protein with a RING finger motif. | Ueki, N., et al. 1999. Biochim Biophys Acta. 1445: 232-6. PMID: 10320776
- The FXXLF motif mediates androgen receptor-specific interactions with coregulators. | He, B., et al. 2002. J Biol Chem. 277: 10226-35. PMID: 11779876
- A putative nuclear receptor coactivator (TMF/ARA160) associates with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the Golgi apparatus. | Mori, K. and Kato, H. 2002. FEBS Lett. 520: 127-32. PMID: 12044884
- Cloning and chromosomal mapping of a human immunodeficiency virus 1 'TATA' element modulatory factor. | Garcia, JA., et al. 1992. Proc Natl Acad Sci U S A. 89: 9372-6. PMID: 1409643
- TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3. | Perry, E., et al. 2004. Oncogene. 23: 8908-19. PMID: 15467733
- TMF/ARA160 downregulates proangiogenic genes and attenuates the progression of PC3 xenografts. | Abrham, G., et al. 2009. Int J Cancer. 125: 43-53. PMID: 19330832
- TMF/ARA160: A key regulator of sperm development. | Lerer-Goldshtein, T., et al. 2010. Dev Biol. 348: 12-21. PMID: 20691678
- TMF/ARA160 Governs the Dynamic Spatial Orientation of the Golgi Apparatus during Sperm Development. | Elkis, Y., et al. 2015. PLoS One. 10: e0145277. PMID: 26701263
- Familial incomplete male pseudohermaphroditism, type 2. Decreased dihydrotestosterone formation in pseudovaginal perineoscrotal hypospadias. | Walsh, PC., et al. 1974. N Engl J Med. 291: 944-9. PMID: 4413434
- Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism. | Imperato-McGinley, J., et al. 1974. Science. 186: 1213-5. PMID: 4432067
- The androgen receptor: an overview. | Zhou, ZX., et al. 1994. Recent Prog Horm Res. 49: 249-74. PMID: 8146426
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARA160 Antibody (C-10) | sc-398411 | 200 µg/ml | $316.00 | |||
ARA160 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-527775 | 200 µg Ab; 10 µg BP | $354.00 | |||
ARA160 Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-533148 | 200 µg Ab; 20 µg BP | $354.00 | |||
ARA160 Antibody (C-10) AC | sc-398411 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ARA160 Antibody (C-10) HRP | sc-398411 HRP | 200 µg/ml | $316.00 | |||
ARA160 Antibody (C-10) FITC | sc-398411 FITC | 200 µg/ml | $330.00 | |||
ARA160 Antibody (C-10) PE | sc-398411 PE | 200 µg/ml | $343.00 | |||
ARA160 Antibody (C-10) Alexa Fluor® 488 | sc-398411 AF488 | 200 µg/ml | $357.00 | |||
ARA160 Antibody (C-10) Alexa Fluor® 546 | sc-398411 AF546 | 200 µg/ml | $357.00 | |||
ARA160 Antibody (C-10) Alexa Fluor® 594 | sc-398411 AF594 | 200 µg/ml | $357.00 | |||
ARA160 Antibody (C-10) Alexa Fluor® 647 | sc-398411 AF647 | 200 µg/ml | $357.00 | |||
ARA160 Antibody (C-10) Alexa Fluor® 680 | sc-398411 AF680 | 200 µg/ml | $357.00 | |||
ARA160 Antibody (C-10) Alexa Fluor® 790 | sc-398411 AF790 | 200 µg/ml | $357.00 |