apolipoprotein E/apoE Antibody (WU E-4): sc-53570

apoE Antibody (WU E-4) is a mouse monoclonal IgG1 kappa light chain antibody that specifically targets apolipoprotein E (apoE) from human, mouse, and rat sources. Apolipoprotein E is a crucial protein found in various cellular locations, including the plasma membrane and cytosol, where apoE mediates lipid transport and metabolism. The presence of apoE in plasma lipoproteins is significant for binding, internalization, and breakdown of lipoprotein particles, making apoE essential for cholesterol and lipid homeostasis. As a ligand for receptors like the LDL receptor and the hepatic apoE receptor, apoE facilitates the clearance of cholesterol-rich lipoproteins, thus impacting cardiovascular health. ApoE is synthesized in numerous organs, including the liver and brain, and is present in multiple lipoprotein fractions, including VLDL and HDL. Importantly, apoE is associated with various isoforms, notably E2, E3, and E4, which have functional implications in both lipid metabolism and neurodegenerative diseases. apoE (WU E-4) antibody is recommended for applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP), offering researchers a reliable tool for studying apoE′s role in lipid transport and cellular signaling.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-apolipoprotein E/apoE Antibody (WU E-4) has 13 citations in a variety of scientific publications.

Primary antibodies like Anti-apolipoprotein E/apoE Antibody (WU E-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

apolipoprotein E/apoE Antibody (WU E-4) Specifications

Alternate Product Name: apolipoprotein E

Product Clone Name: WU E-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: apoE

Epitope Species: human

Product Reactivity/Detection: apoE

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of kappa

Research Citations: 13 citations in various scientific publications

Available Conjugates/Forms for apolipoprotein E/apoE Antibody (WU E-4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred apolipoprotein E/apoE antibody is apolipoprotein E/apoE Antibody (A1.4): sc-13521.