apolipoprotein E/apoE Antibody (E-8): sc-393302
- apolipoprotein E/apoE Antibody (E-8) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 293-318 near the C-terminus of apoE of human origin
- apolipoprotein E/apoE Antibody (E-8) is recommended for detection of precursor and mature apoE of human origin by WB, IP, IF and ELISA
- Anti-apolipoprotein E/apoE Antibody (E-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to biotin for WB, IHC(P) and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for apolipoprotein E/apoE Antibody (E-8) for WB applications. This reagent is now offered in a bundle with apolipoprotein E/apoE Antibody (E-8) (see ordering information below).
apoE Antibody (E-8) is a mouse monoclonal IgG1 kappa light chain antibody that recognizes an epitope near the C-terminus of apolipoprotein E (apoE), specifically between amino acids 293-318 in human samples. Apolipoprotein E (apoE) plays a crucial role in lipid metabolism, particularly in the binding, internalization, and catabolism of lipoprotein particles. One of the significant post-translational modifications of apoE is glycosylation, which impacts stability and interaction with receptors such as the LDL receptor. This modification is vital as glycosylation affects apoE′s ability to mediate cholesterol transport and lipid clearance, processes that are central to maintaining lipid homeostasis and preventing lipid accumulation in tissues. Additionally, phosphorylation of apoE at specific sites can influence interaction with lipoproteins, further regulating biological activity. anti-apoE antibody (E-8) is reactive with both precursor and mature forms of apoE and has been validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). apoE monoclonal antibody (E-8) serves as an excellent tool for studying regulation and post-translational modifications of apoE, which are critical for understanding roles in lipid metabolism and associated diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apolipoprotein E/apoE Antibody (E-8) | sc-393302 | 200 µg/ml | $316.00 | |||
apolipoprotein E/apoE Antibody (E-8): m-IgG Fc BP-HRP Bundle | sc-526238 | 200 µg Ab; 10 µg BP | $354.00 | |||
apolipoprotein E/apoE Antibody (E-8) AC | sc-393302 AC | 500 µg/ml, 25% agarose | $416.00 | |||
apolipoprotein E/apoE Antibody (E-8) HRP | sc-393302 HRP | 200 µg/ml | $316.00 | |||
apolipoprotein E/apoE Antibody (E-8) FITC | sc-393302 FITC | 200 µg/ml | $330.00 | |||
apolipoprotein E/apoE Antibody (E-8) PE | sc-393302 PE | 200 µg/ml | $343.00 | |||
apolipoprotein E/apoE Antibody (E-8) Alexa Fluor® 488 | sc-393302 AF488 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (E-8) Alexa Fluor® 546 | sc-393302 AF546 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (E-8) Alexa Fluor® 594 | sc-393302 AF594 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (E-8) Alexa Fluor® 647 | sc-393302 AF647 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (E-8) Alexa Fluor® 680 | sc-393302 AF680 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (E-8) Alexa Fluor® 790 | sc-393302 AF790 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (E-8) B | sc-393302 B | 200 µg/ml | $320.00 | |||
apolipoprotein E/apoE (E-8) Neutralizing Peptide | sc-393302 P | 100 µg/0.5 ml | $68.00 |