apoC-I Antibody (Y-13): sc-101263

apoC-I Antibody (Y-13) is a mouse monoclonal IgG1 kappa light chain antibody that detects apoC-I of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). anti-apoC-I antibody (Y-13) is available as the non-conjugated isotype antibody. apoC-I plays a crucial role in lipid metabolism, particularly in the modulation of triglyceride-rich lipoproteins, which are essential for maintaining lipid homeostasis in the body. apoC-I is primarily synthesized in the liver and is activated during the differentiation of monocytes into macrophages, highlighting its importance in inflammatory responses and lipid transport. The human apoC-I gene, located on chromosome 19q13.2, is part of a gene family that includes apoC-II, apoC-III, and apoC-IV, each contributing to the regulation of lipoprotein metabolism. apoC-I interacts with other apolipoproteins and enzymes, influencing the activity of lipoprotein lipase, which is vital for the hydrolysis of triglycerides in plasma. Understanding the function and interactions of apoC-I is essential for elucidating the mechanisms underlying lipid disorders and cardiovascular diseases.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

apoC-I Antibody (Y-13) References:

1. Insights into apolipoprotein C metabolism from transgenic and gene-targeted mice.  |  Jong, MC. and Havekes, LM. 2000. Int J Tissue React. 22: 59-66. PMID: 10937355
2. Hypertriglyceridemia associated with deficiency of apolipoprotein C-II.  |  Breckenridge, WC., et al. 1978. N Engl J Med. 298: 1265-73. PMID: 565877
3. Identification and characterization of a new human gene (APOC4) in the apolipoprotein E, C-I, and C-II gene locus.  |  Allan, CM., et al. 1995. Genomics. 28: 291-300. PMID: 8530039

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-apoC-I Antibody (Y-13) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-apoC-I Antibody (Y-13) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

apoC-I Antibody (Y-13) Specifications

Alternate Product Name: apoC-I

Product Clone Name: Y-13

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-84

Epitope Target: apoC-I

Epitope Species: human

Product Reactivity/Detection: apoC-I

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for apoC-I Antibody (Y-13): N/A