Apolipoprotein A I/APOA1 Antibody (G-11): sc-376811
- Apolipoprotein A I/APOA1 Antibody (G-11) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 1-267 representing full length apoA-I of human origin
- recommended for detection of apoA-I of human origin by WB, IP, IF, IHC(P) and ELISA
- See Apolipoprotein A I/APOA1 (B-10): sc-376818 for Apolipoprotein A I/APOA1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Apolipoprotein A I/APOA1 Antibody (G-11) for WB and IHC(P) applications. These reagents are now offered in bundles with Apolipoprotein A I/APOA1 Antibody (G-11) (see ordering information below).
ApoA-I Antibody (G-11) is a mouse monoclonal IgG1 antibody that detects apolipoprotein A-I (apoA-I) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ApoA-I is a crucial component of high-density lipoprotein (HDL) in plasma, consisting of 243 amino acids, and plays a vital role in lipid metabolism by promoting the efflux of cholesterol from peripheral tissues to the liver for excretion. This process is essential for maintaining cholesterol homeostasis and preventing atherosclerosis, a condition characterized by the buildup of fats, cholesterol, and other substances in and on the artery walls. Additionally, apoA-I serves as a cofactor for lecithin cholesterol acyltransferase (LCAT), an enzyme that catalyzes the formation of cholesteryl esters, further facilitating the transport and metabolism of lipids. The importance of apoA-I extends beyond its structural role; apoA-I is also involved in the regulation of plasma triglyceride levels and influences the overall lipid profile, making apoA-I a significant target for research in cardiovascular health and metabolic disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Apolipoprotein A I/APOA1 Antibody (G-11) | sc-376811 | 200 µg/ml | $316.00 | |||
Apolipoprotein A I/APOA1 Antibody (G-11): m-IgG Fc BP-HRP Bundle | sc-540649 | 200 µg Ab; 10 µg BP | $354.00 | |||
Apolipoprotein A I/APOA1 Antibody (G-11): m-IgG1 BP-HRP Bundle | sc-542268 | 200 µg Ab; 20 µg BP | $354.00 |