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APNG Antibody (3D1) is a mouse monoclonal IgG2a antibody that detects APNG in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). APNG, or human N-methylpurine-DNA glycosylase, plays a crucial role in the base excision repair pathway, which is essential for maintaining genomic integrity by repairing DNA lesions caused by environmental factors and normal cellular processes. APNG is primarily located in the nucleus, where APNG identifies and excises damaged bases, such as 3-methyladenine, from the DNA strand, thereby preventing mutations that could lead to diseases such as cancer. The efficient functioning of APNG is vital, as APNG ensures that DNA repair mechanisms can promptly address and rectify potential errors, safeguarding the cell′s genetic material. The human APNG gene is located on chromosome 16p13.3 and encodes a 298 amino acid protein, underscoring APNG′s importance in cellular health and stability. Anti-APNG antibody (3D1) is an invaluable tool for researchers studying DNA repair mechanisms and the implications of DNA damage in human health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
APNG Antibody (3D1) | sc-101237 | 100 µg/ml | $333.00 |