Date published: 2025-11-21

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APNG Antibody (3D1): sc-101237

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Datasheets
  • APNG Antibody (3D1) is a mouse monoclonal IgG2a κ, cited in 4 publications, provided at 100 µg/ml
  • raised against recombinant APNG of human origin
  • recommended for detection of APNG of human origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for APNG Antibody (3D1). This work is in progress.

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APNG Antibody (3D1) is a mouse monoclonal IgG2a antibody that detects APNG in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). APNG, or human N-methylpurine-DNA glycosylase, plays a crucial role in the base excision repair pathway, which is essential for maintaining genomic integrity by repairing DNA lesions caused by environmental factors and normal cellular processes. APNG is primarily located in the nucleus, where APNG identifies and excises damaged bases, such as 3-methyladenine, from the DNA strand, thereby preventing mutations that could lead to diseases such as cancer. The efficient functioning of APNG is vital, as APNG ensures that DNA repair mechanisms can promptly address and rectify potential errors, safeguarding the cell′s genetic material. The human APNG gene is located on chromosome 16p13.3 and encodes a 298 amino acid protein, underscoring APNG′s importance in cellular health and stability. Anti-APNG antibody (3D1) is an invaluable tool for researchers studying DNA repair mechanisms and the implications of DNA damage in human health.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

APNG Antibody (3D1)

sc-101237
100 µg/ml
$333.00

Can sc-101237: APNG (3D1) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, sc-101237: APNG (3D1) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Great immunoperoxidase nuclear staining inGreat immunoperoxidase nuclear staining in formalin-fixed, paraffin-embedded human kidney tissue. -SCBT QC
Date published: 2015-05-02
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APNG Antibody (3D1) is rated 5.0 out of 5 by 2.
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