Molecular structure of AP 24534 HCl
AP 24534 HCl (CAS 943319-70-8 free base)
Alternate Names:
Ponatinib (2 x HCl Salt)
Application:
AP 24534 HCl is a salt form of AP 24534 which is a tyrosine kinase inhibitor
CAS Number:
943319-70-8 free base
Molecular Weight:
623.5
Molecular Formula:
C29H27F3N6O•H2Cl2•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
AP 24534 HCl operates as a potent and selective inhibitor of the Bcr-Abl kinase, a key enzyme implicated in the signaling pathways that regulate cell growth and survival. Its mode of action is centered around its affinity for the ATP-binding site of the Bcr-Abl kinase. This interaction disrupts the kinase′s functionality, effectively curtailing the transduction of signals necessary for the proliferation and survival of cells expressing this kinase. The interruption of these pathways by AP 24534 HCl facilitates the induction of apoptosis, thereby ceasing the propagation of affected cells. AP 24534 HCl is noted for its ability to mitigate the challenge posed by resistance to similar inhibitors.
Inhibitor of:
Bcr, FGFR, and Flt.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AP 24534 HCl, 10 mg | sc-396905 | 10 mg | $112.00 | |||
AP 24534 HCl, 50 mg | sc-396905A | 50 mg | $138.00 |