Annexin I Antibody (ANEX 6E4/3): sc-53159
- Annexin I Antibody (ANEX 6E4/3) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against mixture of native membrane proteins from bone tissues of human origin
- recommended for detection of Annexin I of human origin by WB, IP and IF
- See Annexin I (EH17a): sc-12740 for Annexin I antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Annexin I Antibody (ANEX 6E4/3) for WB applications. These reagents are now offered in bundles with Annexin I Antibody (ANEX 6E4/3) (see ordering information below).
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Annexin I Antibody (ANEX 6E4/3) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect Annexin I, also known as ANXA1 and Lipocortin I. Anti-Annexin I antibody (ANEX 6E4/3) is raised against a mixture of native membrane proteins from human bone tissues, ensuring reliable recognition of Annexin I in various experimental applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Annexin I is a member of the annexin family of calcium-binding proteins, characterized by a conserved core domain consisting of four annexin repeats that form a helix-loop-helix structure essential for binding phospholipids in a calcium-dependent manner. The unique N-terminal region of Annexin I contributes to specific interactions with other proteins and cellular structures, facilitating its role in regulating membrane dynamics. Structurally, Annexin I plays a crucial role in maintaining cellular integrity and mediating processes such as endocytosis, exocytosis, and cellular adhesion, which are vital for cellular communication and homeostasis. Functionally, Annexin I is pivotal in the anti-inflammatory response by inhibiting phospholipase A2 (cPLA2), thereby reducing the production of pro-inflammatory eicosanoids. The ability of Annexin I to interact with cellular membranes and regulate signal transduction pathways underscores its importance in various physiological and pathological contexts, including inflammation, cancer, and tissue repair. The precise detection and localization of Annexin I enables researchers to explore its structural and functional roles in detail, advancing our understanding of its contributions to health and disease. Annexin I monoclonal antibody (ANEX 6E4/3) is an indispensable tool for scientists aiming to elucidate the complex mechanisms by which Annexin I influences cellular processes and inflammatory responses, making Annexin I (ANEX 6E4/3) antibody a valuable addition to any research laboratory focused on cellular biology and pathology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Annexin I Antibody (ANEX 6E4/3) | sc-53159 | 200 µg/ml | $316.00 | |||
Annexin I Antibody (ANEX 6E4/3): m-IgG Fc BP-HRP Bundle | sc-538975 | 200 µg Ab; 10 µg BP | $354.00 | |||
Annexin I Antibody (ANEX 6E4/3): m-IgG1 BP-HRP Bundle | sc-541187 | 200 µg Ab; 20 µg BP | $354.00 |