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Molecular structure of Angiotensin II [Sar1 Ile8], CAS Number: 67724-27-0
Angiotensin II [Sar1 Ile8] (CAS 67724-27-0)
Alternate Names:
Sar-Arg-Val-Tyr-Ile-His-Pro-Ile
Application:
Angiotensin II [Sar1 Ile8] is an angiotensin receptor antagonist
CAS Number:
67724-27-0
Purity:
≥95%
Molecular Weight:
968.15
Molecular Formula:
C46H73N13O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Angiotensin II [Sar1 Ile8] is an angiotensin receptor antagonist. Angiotensin II [Sar1 Ile8] has been employed to explore the effects of RAS on cardiovascular, renal, and endocrine functions. Furthermore, it has been instrumental in understanding RAS′s impact on inflammation, the immune system, cell growth, differentiation, and the nervous system.
Angiotensin II [Sar1 Ile8] (CAS 67724-27-0) References
- Carotid Body AT(4) Receptor Expression and its Upregulation in Chronic Hypoxia. | Fung, ML., et al. 2007. Open Cardiovasc Med J. 1: 1-7. PMID: 18949084
- Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog. | Asada, H., et al. 2018. Nat Struct Mol Biol. 25: 570-576. PMID: 29967536
- Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2. | Ridgway, H., et al. 2022. Comput Struct Biotechnol J. 20: 2091-2111. PMID: 35432786
- Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System. | Moore, GJ., et al. 2022. Molecules. 27: PMID: 35956801
- Effect of three angiotensin II antagonists, [Sar1, Thr8]-, [Sar1, Ile8]- and [Sar1, Ala8]angiotensin II on blood pressure and endocrine factors in normal subjects. | Hata, T., et al. 1982. Eur J Clin Pharmacol. 23: 7-10. PMID: 6751836
- Amino acid side chain conformation in angiotensin II and analogs: correlated results of circular dichroism and 1H nuclear magnetic resonance. | Piriou, F., et al. 1980. Proc Natl Acad Sci U S A. 77: 82-6. PMID: 6928653
Inhibitor of:
Angiotensin, and AT2.Activator of:
SEC16L, and Sec23IP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Angiotensin II [Sar1 Ile8], 5 mg | sc-391239 | 5 mg | $151.00 | |||
Angiotensin II [Sar1 Ile8], 10 mg | sc-391239A | 10 mg | $215.00 |