Amodiaquine Antibody (HYB 320-04): sc-57615
- Amodiaquine Antibody (HYB 320-04) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against Amodiaquine coupled to S3
- recommended for detection of Amodiaquine by ELISA; may cross-react with desethylchloroquine (1%)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Amodiaquine Antibody (HYB 320-04). This work is in progress.
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Amodiaquine Antibody (HYB 320-04) is a mouse monoclonal IgG2a antibody that detects Amodiaquine in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Amodiaquine monoclonal antibody (HYB 320-04) recognizes a 4-aminoquinoline compound known for antimalarial properties, functioning primarily by accumulating in parasite lysosomes, which leads to function loss and contributes to schizonticidal activity. This mechanism disrupts the parasite′s ability to metabolize heme, resulting in toxic free heme accumulation, which proves detrimental to malaria-causing organisms. Anti-Amodiaquine antibody (HYB 320-04) helps study how Amodiaquine inhibits heme polymerase activity, underscoring therapeutic potential and highlighting the importance of targeting specific biochemical pathways in malaria treatment. With over 40 years of use as both an antimalarial and anti-inflammatory agent, Amodiaquine remains significant in fighting malaria, although caution is advised due to potential overdose effects, including severe neurological and cardiovascular complications. Amodiaquine (HYB 320-04) antibody serves as an essential tool for researchers studying pharmacodynamics and therapeutic applications of this important compound.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amodiaquine Antibody (HYB 320-04) | sc-57615 | 100 µg/ml | $322.00 |