Aminopeptidase P3 Antibody (A-4): sc-398497

Aminopeptidase P3 Antibody (A-4) is a mouse monoclonal IgG1 antibody that detects Aminopeptidase P3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Aminopeptidase P3, also referred to as APP3 or XPNPEP3, is a 507 amino acid protein that plays a crucial role in protein metabolism by catalyzing the removal of proline-linked N-terminal amino acids from peptides, which is essential for various physiological processes, including protein maturation and degradation. Aminopeptidase P3 is expressed throughout the human body and utilizes manganese as a cofactor, highlighting its importance in enzymatic reactions. Notably, Aminopeptidase P3 exists in three alternatively spliced isoforms, which adds complexity to its functional roles and regulatory mechanisms. The gene encoding Aminopeptidase P3 is located on chromosome 22, a region that is significant not only for its numerous genes but also for its association with various genetic disorders, including Phelan-McDermid syndrome and schizophrenia. The versatility of Aminopeptidase P3 in processing peptides underscores its potential as a therapeutic target and a biomarker in disease states, making anti-Aminopeptidase P3 antibody (A-4) an invaluable tool for researchers studying protein interactions and functions in human health and disease.

The preferred Aminopeptidase P3 antibody is Aminopeptidase P3 Antibody (C-5): sc-393796.