Aminopeptidase P3 Antibody (C-5): sc-393796
- Aminopeptidase P3 Antibody (C-5) is a mouse monoclonal IgG2a κ Aminopeptidase P3 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 102-125 within an internal region of Aminopeptidase P3 of human origin
- Aminopeptidase P3 Antibody (C-5) is recommended for detection of Aminopeptidase P3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and canine
- Anti-Aminopeptidase P3 Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Aminopeptidase P3 Antibody (C-5) for WB applications. These reagents are now offered in bundles with Aminopeptidase P3 Antibody (C-5) (see ordering information below).
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Aminopeptidase P3 Antibody (C-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Aminopeptidase P3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Aminopeptidase P3 antibody (C-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Aminopeptidase P3, also known as APP3 or XPNPEP3, is a 507 amino acid protein that plays a crucial role in protein metabolism by catalyzing the removal of N-terminal amino acids from proteins, particularly those linked to proline. This enzymatic activity is vital for various physiological processes, including protein turnover and regulation of bioactive peptides, which can influence numerous cellular functions. Aminopeptidase P3 is expressed throughout the body and utilizes manganese as a cofactor, highlighting its importance in maintaining proper metabolic functions. Additionally, Aminopeptidase P3 exists in three alternatively spliced isoforms, and its gene is located on chromosome 22, a region associated with several genetic disorders, including Phelan-McDermid syndrome and Neurofibromatosis type 2. Aminopeptidase P3 (C-5) monoclonal antibody in multiple formats serves as a versatile tool for researchers studying the role of this important enzyme in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Aminopeptidase P3 Antibody (C-5) References:
- The DNA sequence of human chromosome 22. | Dunham, I., et al. 1999. Nature. 402: 489-95. PMID: 10591208
- A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. | Bouwmeester, T., et al. 2004. Nat Cell Biol. 6: 97-105. PMID: 14743216
- Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions. | Erşahin, C., et al. 2005. Arch Biochem Biophys. 435: 303-10. PMID: 15708373
- The proteomics of N-terminal methionine cleavage. | Frottin, F., et al. 2006. Mol Cell Proteomics. 5: 2336-49. PMID: 16963780
- Analyses of the associations between the genes of 22q11 deletion syndrome and schizophrenia. | Arinami, T. 2006. J Hum Genet. 51: 1037-1045. PMID: 16969581
- Prediction of protein structural classes using hybrid properties. | Li, W., et al. 2008. Mol Divers. 12: 171-9. PMID: 18953662
- Evaluation of some fluorogenic substrates for continuous assay of aminopeptidase P. | Hawthorne, SJ., et al. 1997. Anal Biochem. 253: 13-7. PMID: 9356135
- Amyloid precursor protein activates phosphotyrosine signaling pathway. | Mook-Jung, I. and Saitoh, T. 1997. Neurosci Lett. 235: 1-4. PMID: 9389581
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aminopeptidase P3 Antibody (C-5) | sc-393796 | 200 µg/ml | $322.00 | |||
Aminopeptidase P3 Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-530583 | 200 µg Ab; 10 µg BP | $361.00 | |||
Aminopeptidase P3 Antibody (C-5): m-IgGκ BP-HRP Bundle | sc-524092 | 200 µg Ab, 40 µg BP | $361.00 | |||
Aminopeptidase P3 Antibody (C-5) AC | sc-393796 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Aminopeptidase P3 Antibody (C-5) HRP | sc-393796 HRP | 200 µg/ml | $322.00 | |||
Aminopeptidase P3 Antibody (C-5) FITC | sc-393796 FITC | 200 µg/ml | $336.00 | |||
Aminopeptidase P3 Antibody (C-5) PE | sc-393796 PE | 200 µg/ml | $349.00 | |||
Aminopeptidase P3 Antibody (C-5) Alexa Fluor® 488 | sc-393796 AF488 | 200 µg/ml | $364.00 | |||
Aminopeptidase P3 Antibody (C-5) Alexa Fluor® 546 | sc-393796 AF546 | 200 µg/ml | $364.00 | |||
Aminopeptidase P3 Antibody (C-5) Alexa Fluor® 594 | sc-393796 AF594 | 200 µg/ml | $364.00 | |||
Aminopeptidase P3 Antibody (C-5) Alexa Fluor® 647 | sc-393796 AF647 | 200 µg/ml | $364.00 | |||
Aminopeptidase P3 Antibody (C-5) Alexa Fluor® 680 | sc-393796 AF680 | 200 µg/ml | $364.00 | |||
Aminopeptidase P3 Antibody (C-5) Alexa Fluor® 790 | sc-393796 AF790 | 200 µg/ml | $364.00 | |||
Aminopeptidase P3 (C-5) Neutralizing Peptide | sc-393796 P | 100 µg/0.5 ml | $69.00 |