Aminoacylase-1 Antibody (D-7): sc-514432

Aminoacylase-1 Antibody (D-7) is a mouse monoclonal IgM antibody that detects Aminoacylase-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Aminoacylase-1, also known as N-acyl-L-amino-acid amidohydrolase or ACY-1, is a crucial enzyme belonging to the metallopeptidase family M20A, characterized by its zinc-binding homodimeric structure. Aminoacylase-1 is predominantly localized in the cytoplasm and plays a vital role in the hydrolysis of N-acylated or N-acetylated amino acids, which is essential for amino acid metabolism and cellular function. Aminoacylase-1 interaction with sphingosine kinase 1 (SphK1) suggests involvement in cellular responses to oxidative stress, highlighting importance in maintaining cellular homeostasis. The gene encoding Aminoacylase-1 is evolutionarily conserved across various species, including fish, frogs, mice, rats, and humans, indicating fundamental biological significance. Deficiencies in Aminoacylase-1 can lead to metabolic and functional defects in the brain, underscoring necessity in neurological health. With diverse applications and critical role in cellular processes, anti-Aminoacylase-1 antibody (D-7) serves as an invaluable tool for researchers studying amino acid metabolism and related pathways.

The preferred Aminoacylase-1 antibody is Aminoacylase-1 Antibody (B-1): sc-271019.