αC-crystallin Antibody (PL-A11): sc-134243
- αC-crystallin Antibody (PL-A11) is a mouse monoclonal mouse IgG2b κ κ provided at 100 µg/ml
- raised against recombinant αC-crystallin protein of human origin
- recommended for detection of αC-crystallin of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for αC-crystallin Antibody (PL-A11). This work is in progress.
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αC-crystallin Antibody (PL-A11) is a mouse monoclonal IgG2b antibody that detects αC-crystallin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). αC-crystallin plays a crucial role in maintaining lens transparency and protecting against protein aggregation, which is vital for proper visual function. αC-crystallin is primarily located in the eye lens, where αC-crystallin helps to stabilize the structure of other crystallins and prevent their denaturation under stress conditions, such as heat. The unique structural features of αC-crystallin, including the ability to form large oligomeric complexes, allow αC-crystallin to function effectively as a molecular chaperone, although αC-crystallin does not renature denatured proteins. Additionally, αC-crystallin interacts with membrane proteins, specifically at the polar-apolar interface, which can influence the mobility of the lipid bilayer, thereby contributing to the overall integrity and functionality of lens cells. With diverse applications and significant biological role, anti-αC-crystallin antibody (PL-A11) serves as an essential tool for researchers studying eye health and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
αC-crystallin Antibody (PL-A11) | sc-134243 | 100 µg/ml | $333.00 |