α1b Tubulin Antibody (1H10): sc-134238

α1b Tubulin Antibody (1H10) is a mouse monoclonal IgG2b kappa light chain antibody that detects α1b Tubulin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). anti-α1b Tubulin antibody (1H10) is offered in a non-conjugated form, allowing for versatile experimental setups. Tubulin, a crucial component of the cytoskeleton, plays a vital role in maintaining cell shape, enabling intracellular transport, and facilitating cell division. Tubulin exists in five distinct forms—α, β, γ, δ, and ε Tubulin—where α and β Tubulins form heterodimers that polymerize into microtubule filaments, essential for various cellular functions. γ Tubulin is integral to the formation of the gammasome, which is critical for microtubule nucleation at the centrosome, thereby influencing cell division and organization. α1b Tubulin interaction with other tubulin isoforms and proteins is essential for the dynamic stability of microtubules, which are involved in processes such as mitosis and intracellular transport. Understanding α1b Tubulin function and interactions is crucial for elucidating its role in cellular architecture and signaling pathways, making α1b Tubulin monoclonal antibody (1H10) an invaluable tool for researchers studying cytoskeletal dynamics and related cellular processes.

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α1b Tubulin Antibody (1H10) References:

1. Presence of the betaII isotype of tubulin in the nuclei of cultured mesangial cells from rat kidney.  |  Walss, C., et al. 1999. Cell Motil Cytoskeleton. 42: 274-84. PMID: 10223634
2. Identification of betaIII- and betaIV-tubulin isotypes in cold-adapted microtubules from Atlantic cod (Gadus morhua): antibody mapping and cDNA sequencing.  |  Modig, C., et al. 1999. Cell Motil Cytoskeleton. 42: 315-30. PMID: 10223637
3. Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function.  |  Chang, P. and Stearns, T. 2000. Nat Cell Biol. 2: 30-5. PMID: 10620804
4. Tubulin immunoreactive neuronal intranuclear inclusions in the human brain.  |  Woulfe, J. and Munoz, D. 2000. Neuropathol Appl Neurobiol. 26: 161-71. PMID: 10840279
5. Alpha-, beta-, and gamma-tubulins: sequence comparisons and structural constraints.  |  Burns, RG. 1991. Cell Motil Cytoskeleton. 20: 181-9. PMID: 1773446
6. Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome.  |  Zheng, Y., et al. 1991. Cell. 65: 817-23. PMID: 1904010
7. Invited review: the role of nucleotide triphosphate in actin and tubulin assembly and function.  |  Weisenberg, RC. 1981. Cell Motil. 1: 485-97. PMID: 6756643
8. Multiple forms of tubulin: different gene products and covalent modifications.  |  Ludueña, RF. 1998. Int Rev Cytol. 178: 207-75. PMID: 9348671
9. Expression of amino- and carboxyl-terminal gamma- and alpha-tubulin mutants in cultured epithelial cells.  |  Leask, A. and Stearns, T. 1998. J Biol Chem. 273: 2661-8. PMID: 9446570

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-α1b Tubulin Antibody (1H10) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-α1b Tubulin Antibody (1H10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

α1b Tubulin Antibody (1H10) Specifications

Alternate Product Name: tubulin alpha 1b

Product Clone Name: 1H10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1-452

Epitope Target: α1b Tubulin

Epitope Species: human

Product Reactivity/Detection: α1b Tubulin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 100 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for α1b Tubulin Antibody (1H10): N/A