Date published: 2025-11-24

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α/β-SNAP Antibody (16D1): sc-65386

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Datasheets
  • α/β-SNAP Antibody (16D1) is a mouse monoclonal IgG2b provided at 100 µg/ml
  • raised against recombinant α-SNAP of human origin
  • recommended for detection of α-SNAP and β-SNAP of mouse, rat and human origin by WB and IP
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for α/β-SNAP Antibody (16D1). This work is in progress.

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    α/β-SNAP Antibody (16D1) is a mouse monoclonal IgG2b antibody that detects α/β-SNAP in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. α/β-SNAP plays a crucial role in regulating synaptic transmission by facilitating SNARE complex assembly, which is essential for synaptic vesicle fusion with presynaptic membrane during neurotransmitter release. This process is vital for proper neuronal communication and is implicated in various neurological functions and disorders. α/β-SNAP interacts with other key proteins involved in exocytosis, such as syntaxins and VAMPs, to mediate N-ethylmaleimide-sensitive factor membrane binding, which is necessary for SNARE complex disassembly after vesicle fusion. By understanding α/β-SNAP interactions and functions, researchers can gain insights into synaptic plasticity mechanisms and potential therapeutic targets for conditions like Alzheimer′s disease and other synaptic dysfunctions. Anti-α/β-SNAP antibody (16D1) serves as an invaluable tool for studying synaptic transmission dynamics and molecular pathways involved in neurotransmitter release.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    α/β-SNAP Antibody (16D1)

    sc-65386
    100 µg/ml
    $316.00

    I am using α/β SNAP (16D1): sc-65386 antibody for immunoprecipitation, how much antibody should I use?

    Asked by: AbPolly
    Thank you for your question. We recommend using 1–10 µl (i.e., 0.2–2 µg) of antibody with 1 ml of cell lysate. However, optimal antibody concentration should be determined by titration. Please find our full immunoprecipitation protocol here: https://www.scbt.com/scbt/resources/protocols/immunoprecipitation-western-blots
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 5 out of 5 by from Strong band in WB in chicken brainStrong band in WB in chicken brain, chicken kidney, rat brain and rat kidney tissue extracts. -SCBT QC
    Date published: 2015-04-15
    Rated 5 out of 5 by from Good specificity in WB in human transfectedGood specificity in WB in human transfected 293T and HeLa whole cell lysates. -SCBT QC
    Date published: 2014-02-15
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    α/β-SNAP Antibody (16D1) is rated 5.0 out of 5 by 2.
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