α-Actin Antibody (5C5): sc-58670
- α-Actin Antibody (5C5) is a mouse monoclonal IgM κ, cited in 34 publications, provided at 200 µg/ml
- recommended for detection of α-skeletal and α-cardiac Actin of mouse, rat, human, rabbit, bovine and Xenopus origin by WB, IP, IF and IHC(P); not recommended for detection of α-Actin from smooth muscle tissue
- See α-Actin (1A4): sc-32251 for α-Actin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for α-Actin Antibody (5C5) for WB and IHC(P) applications. This reagent is now offered in a bundle with α-Actin Antibody (5C5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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α-Actin Antibody (5C5) is a mouse monoclonal IgM antibody that detects α-Actin in mouse, rat, human, rabbit, and bovine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-α-Actin antibody (5C5) is available in a non-conjugated form, providing flexibility for various experimental needs. Actin, a highly conserved protein, plays a pivotal role in cellular structure and motility, constituting up to 50% of total cellular protein in eukaryotic cells. α-Actin monoclonal antibody (5C5) is essential for studying the formation of microvilli and the contractile apparatus in muscle cells, facilitating muscle contraction and cell movement. Actin exists in several isoforms, with α-Actin being specifically expressed in muscle tissues, while β-Actin and γ-Actin are predominant in non-muscle cells. The organization of the Actin cytoskeleton is intricately regulated by members of the small GTPase family, including Rho, Rac, and Cdc42, which coordinate the assembly of Actin stress fibers, the accumulation of Actin filaments at the plasma membrane, and the formation of filopodia, respectively. Understanding the dynamics of α-Actin and its interactions is crucial for elucidating muscle function and the underlying mechanisms of various diseases, making α-Actin (5C5) antibody an invaluable tool for researchers in the field.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Actin Antibody (5C5) | sc-58670 | 200 µg/ml | $316.00 | |||
α-Actin Antibody (5C5): m-IgGκ BP-HRP Bundle | sc-550733 | 200 µg Ab; 40 µg BP | $354.00 |