α-2 antiplasmin Antibody (JJ-16): sc-73658
- α-2 antiplasmin Antibody (JJ-16) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against full length recombinant α-2 antiplasmin of human origin
- recommended for detection of α-2 antiplasmin of human origin by WB, IP and ELISA; non cross-reactive with AAT, AACT, kallistatin or PAI-3
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for α-2 antiplasmin Antibody (JJ-16). This work is in progress.
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α-2 antiplasmin Antibody (JJ-16) is a mouse monoclonal IgG2a antibody that detects α-2 antiplasmin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). α-2 antiplasmin is a crucial serine proteinase inhibitor that plays a significant role in the regulation of fibrinolysis, which is the process of breaking down blood clots. α-2 antiplasmin is primarily located in the plasma and is secreted by the liver, where α-2 antiplasmin acts to inhibit plasmin, the enzyme responsible for clot degradation. α-2 antiplasmin′s location in the bloodstream enables rapid response to clot formation and dissolution, ensuring that the balance between coagulation and fibrinolysis is maintained. By competing with plasminogen for binding sites on fibrin, α-2 antiplasmin prevents excessive clot breakdown, which is vital for preventing bleeding disorders. Impaired function or reduced levels of α-2 antiplasmin can lead to an increased risk of bleeding, highlighting α-2 antiplasmin′s essential role in hemostasis. With specificity for human α-2 antiplasmin, anti-α-2 antiplasmin antibody (JJ-16) is an invaluable tool for researchers studying coagulation pathways and related disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-2 antiplasmin Antibody (JJ-16) | sc-73658 | 100 µg/ml | $322.00 |