Alkaline Phosphatase Antibody (G-9): sc-398461
- Alkaline Phosphatase Antibody (G-9) is a mouse monoclonal IgG1 κ, cited in 10 publications, provided at 200 µg/ml
- raised against amino acids 31-330 mapping near the N-terminus of PLAP of human origin
- recommended for detection of PLAP, ALPPL2 and IAP of mouse, rat and human origin by WB, IP, IF and ELISA
- See PLAP (8B6): sc-47691 for Alkaline Phosphatase antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Alkaline Phosphatase Antibody (G-9) for WB applications. These reagents are now offered in bundles with Alkaline Phosphatase Antibody (G-9) (see ordering information below).
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Alkaline Phosphatase Antibody (G-9) is a mouse monoclonal IgG1 antibody that detects alkaline phosphatase (ALP) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ALP (G-9) antibody recognizes a crucial enzyme that plays a significant role in dephosphorylating various molecules, essential for processes such as bone mineralization and cellular signaling. ALP monoclonal antibody (G-9) targets an enzyme particularly important in the placenta, where ALP aids in the transport of fatty acids and immunoglobulins across the plasma membrane, supporting fetal development and immune function. The presence of ALP in the serum of pregnant women and ectopic expression in certain cancers, including ovarian and testicular tumors, highlights ALP′s potential as a biomarker for both normal physiological processes and pathological conditions. Anti-ALP antibody (G-9) provides reliable detection and quantification of ALP, making this antibody an invaluable tool for researchers studying ALP′s diverse roles in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Alkaline Phosphatase Antibody (G-9) References:
- Structure and mechanism of alkaline phosphatase. | Coleman, JE. 1992. Annu Rev Biophys Biomol Struct. 21: 441-83. PMID: 1525473
- Alkaline phosphatase and tumour inhibition. | FLEMING, RF. and PECZENIK, O. 1948. Nature. 162: 338. PMID: 18934247
- Mutation of a single amino acid converts germ cell alkaline phosphatase to placental alkaline phosphatase. | Watanabe, T., et al. 1991. J Biol Chem. 266: 21174-8. PMID: 1939159
- Prophylactic treatment with alkaline phosphatase in cardiac surgery induces endogenous alkaline phosphatase release. | Kats, S., et al. 2012. Int J Artif Organs. 35: 144-51. PMID: 22395920
- Alkaline phosphatase in stem cells. | Štefková, K., et al. 2015. Stem Cells Int. 2015: 628368. PMID: 25767512
- Alkaline Phosphatase and Hypophosphatasia. | Millán, JL. and Whyte, MP. 2016. Calcif Tissue Int. 98: 398-416. PMID: 26590809
- Alkaline Phosphatase-Triggered Simultaneous Hydrogelation and Chemiluminescence. | Hai, Z., et al. 2017. J Am Chem Soc. 139: 1041-1044. PMID: 28064496
- Dephosphorylation of DNA Fragments with Alkaline Phosphatase. | Green, MR. and Sambrook, J. 2020. Cold Spring Harb Protoc. 2020: 100669. PMID: 32747587
- Alkaline phosphatase in women with osteoporosis. | Hulth, AG., et al. 1979. Acta Med Scand. 206: 201-3. PMID: 495227
- Neutrophil alkaline phosphatase in pregnancy. | Beal, RW., et al. 1967. J Clin Pathol. 20: 749-51. PMID: 5602987
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Alkaline Phosphatase Antibody (G-9) | sc-398461 | 200 µg/ml | $316.00 | |||
Alkaline Phosphatase Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-538448 | 200 µg Ab; 10 µg BP | $354.00 | |||
Alkaline Phosphatase Antibody (G-9): m-IgGκ BP-HRP Bundle | sc-536066 | 200 µg Ab; 40 µg BP | $354.00 | |||
Alkaline Phosphatase Antibody (G-9): m-IgG1 BP-HRP Bundle | sc-545707 | 200 µg Ab; 20 µg BP | $354.00 |