Aldosterone Antibody (10/42133): sc-57023

Aldosterone Antibody (10/42133) is a mouse monoclonal IgG1 antibody that detects Aldosterone in non-species reactive applications such as enzyme-linked immunosorbent assay (ELISA). Anti-Aldosterone antibody (10/42133) is available as a non-conjugated format, providing researchers with a reliable tool for studying this crucial steroid hormone. Aldosterone plays a vital role in maintaining electrolyte balance and regulating blood pressure by influencing sodium and potassium levels in the body. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal cortex and acts primarily on the distal tubules and collecting ducts of the kidneys. By promoting sodium reabsorption and potassium excretion, Aldosterone helps to control extracellular fluid volume and blood pressure. Aldosterone has shown significant effects beyond the kidneys, including involvement in inflammatory processes and tissue remodeling, which can lead to conditions such as fibrosis and cardiovascular diseases. Aldosterone secretion is tightly controlled by factors such as plasma angiotensin II, adrenocorticotropic hormone (ACTH), and potassium levels, with production exhibiting a diurnal rhythm. This multifaceted role of Aldosterone underscores its importance in both physiological and pathological processes, making Aldosterone monoclonal antibody (10/42133) an essential reagent for researchers investigating its diverse functions.

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Aldosterone Antibody (10/42133) References:

1. On the mechanism of action of aldosterone on sodium transport: the role of protein synthesis. 1963.  |  Edelman, I., et al. 1999. J Am Soc Nephrol. 10: 675-81. PMID: 10073619
2. Cardiovascular endocrinology 1: aldosterone function in diabetes mellitus: effects on cardiovascular and renal disease.  |  McFarlane, SI. and Sowers, JR. 2003. J Clin Endocrinol Metab. 88: 516-23. PMID: 12574172
3. 50th anniversary of aldosterone.  |  Williams, JS. and Williams, GH. 2003. J Clin Endocrinol Metab. 88: 2364-72. PMID: 12788829
4. [Aldosterone function in the nephrotic syndrome & the use of corticosterolds in the treatment of this disease].  |  FABRE, J., et al. 1958. Brux Med. 38: 1457-83. PMID: 13572970
5. Aldosterone and DNA: the 50th anniversary.  |  Fuller, PJ. 2004. Trends Endocrinol Metab. 15: 143-6. PMID: 15109611
6. [Salt wasting syndrome caused by congenital, insufficient synthesis or aldosterone function--etiology, diagnosis and management].  |  Basiak, A., et al. 2005. Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw. 11: 103-8. PMID: 15996340
7. [Present state of the dynamic studies of the adrenal cortex (excepting and aldosterone function)].  |  Bricaire, H., et al. 1968. Presse Med (1893). 76: 2157-60. PMID: 4305257
8. The mechanism of aldosterone function.  |  Ludens, JH. and Fanestil, DD. 1976. Pharmacol Ther B. 2: 371-412. PMID: 8795
9. The ups and downs of the renin-angiotensin-aldosterone system since Tigerstedt's first discovery of renin.  |  Vallotton, MB. 1998. Endocr Res. 24: 781-8. PMID: 9888578

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Aldosterone Antibody (10/42133) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Aldosterone Antibody (10/42133) Specifications

Alternate Product Name: Aldosterone

Product Clone Name: 10/42133

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Aldosterone

Epitope Species:

Product Reactivity/Detection: Aldosterone

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Aldosterone Antibody (10/42133): N/A