Aldehyde dehydrogenase 4-A1/P5CDH/ALDH4A1 Antibody (672): sc-100499
- Aldehyde dehydrogenase 4-A1/P5CDH/ALDH4A1 Antibody (672) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant ALDH4A1 of human origin
- recommended for detection of ALDH4A1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Aldehyde dehydrogenase 4-A1/P5CDH/ALDH4A1 Antibody (672). This work is in progress.
ALDH4A1 Antibody (672) is a mouse monoclonal IgG1 antibody that detects ALDH4A1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ALDH4A1, also known as P5CD (Delta-1-pyrroline-5-carboxylate dehydrogenase), plays a crucial role in the proline degradation pathway by catalyzing the conversion of Delta-1-pyrroline-5-carboxylate (P5C) to glutamate within the mitochondrial matrix. This enzymatic activity is vital for maintaining cellular homeostasis and regulating proline levels, which are essential for various metabolic processes, including the synthesis of neurotransmitters and the detoxification of harmful aldehydes. Dysregulation of ALDH4A1 due to genetic mutations can lead to hyperprolinemia type II, a condition marked by elevated levels of proline and P5C, which can result in severe neurological consequences such as mental retardation and seizures. Anti-ALDH4A1 antibody (672) serves as an invaluable tool for researchers investigating the functional implications of ALDH4A1 in metabolic disorders and potential role in neurodevelopmental diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aldehyde dehydrogenase 4-A1/P5CDH/ALDH4A1 Antibody (672) | sc-100499 | 100 µg/ml | $339.00 |