AK7 Antibody (D-5): sc-393337
- AK7 Antibody (D-5) is a mouse monoclonal IgG1 κ AK7 antibody provided at 200 µg/ml
- raised against amino acids 518-723 mapping at the C-terminus of AK7 of human origin
- AK7 Antibody (D-5) is recommended for detection of AK7 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-AK7 Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for AK7 Antibody (D-5). This work is in progress.
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AK7 Antibody (D-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects AK7 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AK7 (D-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. AK7, also known as adenylate kinase 7, is a 723 amino acid enzyme that plays a crucial role in cellular energy homeostasis by catalyzing the conversion of one adenosine triphosphate (ATP) and one adenosine monophosphate (AMP) into two adenosine diphosphate (ADP) molecules. This enzymatic activity is vital for maintaining the balance of adenine nucleotides within the cell, which is essential for various metabolic processes and cellular signaling pathways. The gene encoding AK7 is located on human chromosome 14, a region that is significant not only for its numerous genes but also for its association with critical health conditions, including Alzheimer′s disease and a1-antitrypsin deficiency. Using AK7 (D-5) antibody in research can provide insights into the functional dynamics of adenylate kinases and their implications in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
AK7 Antibody (D-5) References:
- The DNA sequence and analysis of human chromosome 14. | Heilig, R., et al. 2003. Nature. 421: 601-7. PMID: 12508121
- A presenilin 1 R278I mutation presenting with language impairment. | Godbolt, AK., et al. 2004. Neurology. 63: 1702-4. PMID: 15534260
- Pathological and physiological functions of presenilins. | Vetrivel, KS., et al. 2006. Mol Neurodegener. 1: 4. PMID: 16930451
- Presenilin-1 mutation E318G and familial Alzheimer's disease in the Italian population. | Albani, D., et al. 2007. Neurobiol Aging. 28: 1682-8. PMID: 16952411
- A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation. | Martín-Subero, JI., et al. 2007. Leukemia. 21: 1532-44. PMID: 17495977
- The genetics of very early onset Alzheimer disease. | Filley, CM., et al. 2007. Cogn Behav Neurol. 20: 149-56. PMID: 17846513
- The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency. | Cruz, PE., et al. 2007. Pharmacogenomics. 8: 1191-8. PMID: 17924834
- Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management. | Stolk, J., et al. 2006. Int J Chron Obstruct Pulmon Dis. 1: 151-60. PMID: 18046892
- Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing. | Dzeja, P. and Terzic, A. 2009. Int J Mol Sci. 10: 1729-1772. PMID: 19468337
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AK7 Antibody (D-5) | sc-393337 | 200 µg/ml | $322.00 | |||
AK7 Antibody (D-5) AC | sc-393337 AC | 500 µg/ml, 25% agarose | $424.00 | |||
AK7 Antibody (D-5) HRP | sc-393337 HRP | 200 µg/ml | $322.00 | |||
AK7 Antibody (D-5) FITC | sc-393337 FITC | 200 µg/ml | $336.00 | |||
AK7 Antibody (D-5) PE | sc-393337 PE | 200 µg/ml | $349.00 | |||
AK7 Antibody (D-5) Alexa Fluor® 488 | sc-393337 AF488 | 200 µg/ml | $364.00 | |||
AK7 Antibody (D-5) Alexa Fluor® 546 | sc-393337 AF546 | 200 µg/ml | $364.00 | |||
AK7 Antibody (D-5) Alexa Fluor® 594 | sc-393337 AF594 | 200 µg/ml | $364.00 | |||
AK7 Antibody (D-5) Alexa Fluor® 647 | sc-393337 AF647 | 200 µg/ml | $364.00 | |||
AK7 Antibody (D-5) Alexa Fluor® 680 | sc-393337 AF680 | 200 µg/ml | $364.00 | |||
AK7 Antibody (D-5) Alexa Fluor® 790 | sc-393337 AF790 | 200 µg/ml | $364.00 |